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Plk (F-8) Antibody: sc-17783

 |  Datasheet
  • mouse monoclonal IgG2a; 200 µg/ml
  • raised against amino acids 261-412 mapping to an internal region of Plk of human origin
  • recommended for detection of Plk of mouse, rat and human origin by WB, IP, IF and ELISA
 
Additional Plk Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PLK1 5347 16p12.1 NM_005030 P53350
n/a
Mouse Plk1 18817 7 F3 Q07832
N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Plk (F-8) sc-17783 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Plk siRNA (h) sc-36277 10 µM $258
Plk siRNA (m) sc-36278 10 µM $258
Plk (h)-PR sc-36277-PR 10 µM $23
Plk (m)-PR sc-36278-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Plk shRNA Plasmid (h) sc-36277-SH 20 µg $520
Plk shRNA Plasmid (m) sc-36278-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Plk shRNA (h) Lentiviral Particles sc-36277-V 200 µl $625
Plk shRNA (m) Lentiviral Particles sc-36278-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
A549 Cell Lysate sc-2413 500 µg/200 µl $104
KNRK Whole Cell Lysate sc-2214 500 µg/200 µl $104
Plk (h2): 293T Lysate sc-170528 100µg/200µl $205
Plk (m): 293T Lysate sc-127352 100µg/200µl $205
Plk (h): 293 Lysate sc-111085 100µg/200µl $205

Plk Background Information
Plk (for polo-like kinase) encodes a serine/threonine kinase that is closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo and CDC5 both code for proteins that are involved in regulating the function of the mitotic spindle. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle and both protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.

Plk (F-8) Product Citations
See how others have used Plk (F-8): sc-17783 antibody and or Plk (F-8) antibody conjugates.


26 total citations
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Plk (F-8)
Click on image to enlarge
Plk (F-8): sc-17783. Western blot analysis of Plk expression in HeLa (A), A549 (B) and KNRK (C) whole cell lysates.
Plk siRNA (h): sc-36277. Western blot analysis of Plk expression in non-transfected control (A) and Plk siRNA transfected (B) HeLa cells. Blot probed with Plk (F-8): sc-17783. β Tubulin (D-10): sc-5274 used as specificity and loading control.
Plk (F-8): sc-17783. Western blot analysis of Plk expression in non-transfected: sc-110760 (A) and human Plk transfected: sc-111085 (B) 293 whole cell lysates.
Plk (F-8): sc-17783. Western blot analysis of Plk expression in non-transfected 293T: sc-117752 (A), mouse Plk transfected 293T: sc-127352 (B) and K-562 (C) whole cell lysates.
Plk (F-8): sc-17783. Western blot analysis of Plk expression in K-562 whole cell lysate.
Plk (F-8): sc-17783. Western blot analysis of Plk expression in non-transfected: sc-117752 (A) and human Plk transfected: sc-170528 (B) 293T whole cell lysates.
Plk (F-8): sc-17783. Western blot analysis of Plk expression in non-transfected: sc-110760 (A) and human Plk transfected: sc-111085 (B) 293 whole cell lysates.
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