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Plk Antibody (F-8): sc-17783

 |  Datasheet

(Based on data analysis)

  • Plk Antibody (F-8) is a mouse monoclonal IgG2a provided at 200 µg/ml
  • raised against amino acids 261-412 mapping to an internal region of Plk of human origin
  • recommended for detection of Plk of mouse, rat and human origin by WB, IP, IF and ELISA
  • See 33 citations for Plk Antibody (F-8)
 
Full-length Plk protein sequence with immunogen highlighted:
MSAAVTAGKLARAPADPGKAGVPGVAAPGAPAAAPPAKEIPEVLVDPRSRRRYVRGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFEDNDFVFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHINPVAASLIQKMLQTDPTARPTINELLNDEFFTSGYIPARLPITCLTIPPRFSIAPSSLDPSNRKPLTVLNKGLENPLPERPREKEEPVVRETGEVVDCHLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYGLGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSLMKKITLLKYFRNYMSEHLLKAGANITPREGDELARLPYLRTWFRTRSAIILHLSNGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKELASRLRYARTMVDKLLSSRSASNRLKAS

See additional Plk Antibodies.

Also see Plk Inhibitors for functional analysis of cellular responses to Plk.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Plk Antibody (F-8) sc-17783 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Plk siRNA (h) sc-36277 10 µM $258
Plk siRNA (m) sc-36278 10 µM $258
Plk (h)-PR sc-36277-PR 10 µM, 20 µl $23
Plk (m)-PR sc-36278-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Plk shRNA Plasmid (h) sc-36277-SH 20 µg $520
Plk shRNA Plasmid (m) sc-36278-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Plk shRNA (h) Lentiviral Particles sc-36277-V 200 µl $625
Plk shRNA (m) Lentiviral Particles sc-36278-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
A549 Cell Lysate sc-2413 500 µg/200 µl $104
KNRK Whole Cell Lysate sc-2214 500 µg/200 µl $104
Plk (h2): 293T Lysate sc-170528 100 µg/200 µl $205
Plk (m): 293T Lysate sc-127352 100 µg/200 µl $205
Plk (h): 293 Lysate sc-111085 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PLK1 5347 16p12.1 NM_005030 P53350
 n/a
Mouse Plk1 18817 7 F3 Q07832
 N/A
 

Plk (for polo-like kinase) encodes a serine/threonine kinase that is closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo and CDC5 both code for proteins that are involved in regulating the function of the mitotic spindle. Plk protein accumulates in the cell during the S and G2 phases of the cell cycle and both protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Plk expression is detectable in mitotically active tissues such as colon and placenta, as well as in tumors of various origins. It has also been suggested that Plk may serve as a marker of cell proliferation.

Plk Antibody (F-8) Product Citations
See how others have used Plk Antibody (F-8) and or Plk Antibody (F-8) conjugates.


33 total citations
Loading citations.
 
Plk Antibody (F-8) Data
Click on image to enlarge
sc-17783
Plk (F-8): sc-17783. Western blot analysis of Plk expression in HeLa (A), A549 (B) and KNRK (C) whole cell lysates.
sc-17783
Plk siRNA (h): sc-36277. Western blot analysis of Plk expression in non-transfected control (A) and Plk siRNA transfected (B) HeLa cells. Blot probed with Plk (F-8): sc-17783. β Tubulin (D-10): sc-5274 used as specificity and loading control.
sc-17783
Plk (F-8): sc-17783. Western blot analysis of Plk expression in non-transfected: sc-110760 (A) and human Plk transfected: sc-111085 (B) 293 whole cell lysates.
sc-17783
Plk (F-8): sc-17783. Western blot analysis of Plk expression in non-transfected 293T: sc-117752 (A), mouse Plk transfected 293T: sc-127352 (B) and K-562 (C) whole cell lysates.
sc-17783
Plk (F-8): sc-17783. Western blot analysis of Plk expression in K-562 whole cell lysate.
sc-17783
Plk (F-8): sc-17783. Western blot analysis of Plk expression in non-transfected: sc-117752 (A) and human Plk transfected: sc-170528 (B) 293T whole cell lysates.
sc-17783
Plk (F-8): sc-17783. Western blot analysis of Plk expression in non-transfected: sc-110760 (A) and human Plk transfected: sc-111085 (B) 293 whole cell lysates.
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