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home » Cell Cycle Proteins » Rad Antibody / Rad Antibodies » Rad17 (H-3): sc-17761

Rad17 (H-3) Antibody: sc-17761

  |  Datasheet
  • mouse monoclonal IgG1; 200 µg/ml
  • raised against amino acids 371-670 of Rad17 of human origin
  • recommended for detection of Rad17 of human origin by WB, IP, PAR, ELISA
 
Additional Rad Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human RAD17 5884 5q13.2 NM_002873, NM_133338, NM_133339, NM_133340, NM_133341, NM_133342, NM_133343, NM_133344 O75943
 603139
Mouse Rad17 19356 13 D1 NM_001044371, NM_011233 Q6NXW6
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Rad17 (H-3) sc-17761 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Rad17 siRNA (h) sc-36358 10 µM $258
Rad17 siRNA (m) sc-36359 10 µM $258
Rad17 (h)-PR sc-36358-PR 10 µM $23
Rad17 (m)-PR sc-36359-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Rad17 shRNA Plasmid (h) sc-36358-SH 20 µg $520
Rad17 shRNA Plasmid (m) sc-36359-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Rad17 shRNA (h) Lentiviral Particles sc-36358-V 200 µl $625
Rad17 shRNA (m) Lentiviral Particles sc-36359-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa nuclear extract sc-2120 1000 µg $143
Jurkat nuclear extract sc-2132 1000 µg $143
K-562 nuclear extract sc-2130 1000 µg $143
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
Rad17 (m): 293T Lysate sc-122937 100µg/200µl $205

Rad17 Background Information
DNA damage results in the arrest of cell cycle progression, allowing the damaged DNA to be repaired prior to replication. Checkpoints exist at several cell cycle phase transitions to maintain this genetic integrity. Rad9, Rad17, Rad24 and Mec3 are involved in activating the G1 and G2 checkpoints. Pol2 (also known as Dun2), encoding the catalytic subunit of DNA polymerase epsilon, plays a role in activating the S phase checkpoint. The protein kinase Rad53 (also designated Spk1, Mec2 or Sad1) is essential for both G2 and S phase arrest. Activation of Rad53 is regulated by Mec1 (also known as Esr1 and Sad3), a homolog of the human ATM protein. Pds1 and Mad2 both regulate checkpoints associated with incomplete spindle replication. Dun1, another protein kinase, plays a role in transducing the DNA damage signal.

Rad17 (H-3) Product Citations
See how others have used Rad17 (H-3): sc-17761 antibody and or Rad17 (H-3) antibody conjugates.


2 total citations
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Rad17 (H-3)
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sc-17761
Rad17 (H-3): sc-17761. Western blot analysis of Rad17 expression in HeLa (A) and Jurkat (B) nuclear extracts.
sc-17761
Rad17 siRNA (h): sc-36358. Western blot analysis of Rad17 expression in non-transfected control (A) and Rad17 siRNA transfected (B) HeLa cells. Blot probed with Rad17 (H-3): sc-17761. Actin (I-19): sc-1616 used as specificity and loading control.
sc-17761
Rad17 (H-3): sc-17761 Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis cancer showing nuclear staining of tumor cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
sc-17761
Rad17 (H-3): sc-17761. Western blot analysis of Rad17 expression in non-transfected 293T: sc-117752 (A), human Rad17 transfected 293T: sc-114889 (B) and HeLa (C) whole cell lysates.
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