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Msx-1 Antibody (E-20): sc-17727

 |  Datasheet

(Based on data analysis)
  • Msx-1 Antibody (E-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of Msx-1 of human origin
  • recommended for detection Msx-1 of mouse, rat and human origin by WB, IF and ELISA
  • blocking peptide, sc-17727 P
  • TransCruz reagent for Gel Supershift and ChIP applications sc-17727 X, 200 µg/0.1 ml
 

See additional Msx Antibodies including Msx-2, Msx-1, Msx and Msx-3.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   Gel Shift   ChIP   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Msx-1 Antibody (E-20) sc-17727 200 µg/ml $279
Msx-1 (E-20) P sc-17727 P
(peptide)
 100 µg/0.5 ml $61
Msx-1 Antibody (E-20) X sc-17727 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Msx-1 siRNA (h) sc-43945 10 µM $258
Msx-1 siRNA (m) sc-149665 10 µM $258
Msx-1 (h)-PR sc-43945-PR 10 µM, 20 µl $23
Msx-1 (m)-PR sc-149665-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Msx-1 shRNA Plasmid (h) sc-43945-SH 20 µg $520
Msx-1 shRNA Plasmid (m) sc-149665-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Msx-1 shRNA (h) Lentiviral Particles sc-43945-V 200 µl $625
Msx-1 shRNA (m) Lentiviral Particles sc-149665-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MSX1 4487 4p16.2 NM_002448 P28360
 608874
Mouse Msx1 17701 5 B3 P13297
 N/A
 

Msx homeobox genes encode for transcription factors that control morphogenesis and are expressed at sites of epithelial-mesenchymal interaction during embryogenesis, such as the tooth. Two of these genes, Msx-1 and Msx-2, are key factors for the development of tooth and craniofacial skeleton. Msx-1 also down-regulates a master gene of skeletal cells differentiation. Msx-1 and Msx-2 contribute to the initial patterning of dentition as well as playing a pivotal role in terminal cell differentiation. In addition, Msx-1 and Msx-2 are expressed in the epidermis, hair follicles and fibroblasts of the developing fetal skin (4). In adult skin, Msx-1 and Msx-2 expression is confined to epithelially derived structures. Msx-2 is detected as a diffuse cytoplasmic signal in fetal epidermis and portions of the hair follicle and dermis, but is localized to the nucleus in the adult epidermis (4). Msx-1 and Msx-2 are also expressed during critical developmental stages of neural tube and neural crest, suggesting that these genes play an important role in organogenesis (5).