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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the C-terminus of Sox-2 of human origin
- recommended for detection of Sox-2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
- blocking peptide, sc-17320 P
- TransCruz reagent for Gel Supershift and ChIP applications, sc-17320 X, 200 µg/0.1 ml
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
SOX2 |
6657 |
3q26.33 |
NM_003106 |
P48431
|
206900 |
| Mouse |
Sox2 |
20674 |
3 A3 |
|
P48432
|
N/A |
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Sox-2 Background Information
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
| Sox-2 (Y-17) Product Citations |
See how others have used Sox-2 (Y-17): sc-17320 antibody and or Sox-2 (Y-17) antibody conjugates.
42 total citations Loading citations.
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Sox-2 (Y-17)
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Sox-2 (Y-17): sc-17320. Western blot analysis of Sox-2 expression in human (A) and mouse (B) embryonic stem cell lysates. Kindly provided by Dr. Nobuaki Kikyo, Stem Cell Institute, University of Minnesota.
Sox-2 (Y-17): sc-17320. Immunofluorescence staining of paraformaldehyde-fixed mouse embryonic stem cells showing Hoechst nuclear staining (A) and nuclear localization (B). Kindly provided by Dr. Nobuaki Kikyo, Stem Cell Institute, University of Minnesota.
Sox-2 (Y-17): sc-17320. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cervix tissue showing nuclear and cytoplasmic staining of squamous epithelial cells.
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