epitope mapping near the C-terminus of ESE-1 of human origin
recommended for detection of ESE-1 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including canine, bovine and avian
blocking peptide, sc-17306 P
TransCruz reagent for Gel Supershift and ChIP applications, sc-17306 X, 200 µg/0.1 ml
ESE-1 Background Information ESE-1, a member of the Ets family of transcription factors, critically regulates epithelial cell differentiation and mediates vascular inflammation. ESE-1 is strongly expressed in vascular endothelium and smooth muscle cells where it is induced in response to inflammatory cytokines and lipopolysaccharides, interacts with NF-KappaB to induce nitric oxide synthase, and is induced during terminal differentiation of epidermal and primary keratinocytes. In addition, ESE-1 is upregulated upon differentiation of corneal epithelium and interacts with Sp1 and AP-1 proteins to induce squamous differentiation marker expression in bronchial epithelial cells.
ESE-1 (C-20) Product Citations
See how others have used ESE-1 (C-20): sc-17306 antibody and or ESE-1 (C-20) antibody conjugates.