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- goat polyclonal IgG, 200 µg/ml
- epitope mapping within an internal region of BSEP of human origin
- recommended for detection of BSEP of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
- blocking peptide, sc-17292 P
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
ABCB11 |
8647 |
2q24.3 |
NM_003742 |
O95342
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603201 |
| Mouse |
Abcb11 |
27413 |
2 C2 |
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Q9QY30
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N/A |
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BSEP Background Information
ATP-binding cassette (ABC) transporters are an evolutionarily conserved family of proteins that catalyze the transport of molecules across extra- and intracellular membranes through the energy of ATP hydrolysis. ABC genes comprise seven subfamilies, designated ABC1, Mdr/TAP, MRP, ALD, OABP, GCN20 and White. The secretion of bile salt molecules from blood into bile is a major driving force for bile formation. Bile salt export pump (BSEP) is a member of the Mdr/TAP subfamily of ABC transporters that mediates the transport of bile acids across the hepatocyte canalicular membrane and regulates bile acid-dependent bile secretion. BSEP contains putative phosphorylation sites for protein kinase A, protein kinase C (PKC) and Ca2+-calmodulin dependent kinase II, whose regulation may be dependent on bile salt concentration.
| BSEP (N-16) Product Citations |
See how others have used BSEP (N-16): sc-17292 antibody and or BSEP (N-16) antibody conjugates.
5 total citations Loading citations.
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BSEP (N-16)
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BSEP (N-16): sc-17292. Western blot analysis of BSEP expression in NIH/3T3 whole cell lysate.
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