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p-β2-AR Antibody (Tyr 141): sc-17275

 |  Datasheet

(Based on data analysis)

  • p-β2-AR Antibody (Tyr 141) is a goat polyclonal IgG provided at 200 µg/ml; also available as rabbit poloclonal IgG provided at 200 µg/ml, sc-17275-R
  • epitope corresponding to a short amino acid sequence containing phosphorylated Tyr 141 of β2 adrenergic receptor of human origin
  • recommended for detection of Tyr 141 phosphorylated β2 adrenergic receptor of mouse, rat and human origin WB, IF and ELISA; also reactive with additional species, including equine, canine and avian
  • blocking peptide, sc-17275 P
 

See additional AR Antibodies including AR, alpha1A-AR, alpha1B-AR, alpha1D-AR, beta1-AR, alpha2A-AR, alpha2B-AR, alpha2C-AR, beta2-AR and beta3-AR.

Also see beta2-AR Inhibitors or beta2-AR Activators for functional analysis of cellular responses to beta2-AR.


Ordering InformationGene Info
Recommended Support Products:
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WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-β2-AR Antibody (Tyr 141) sc-17275 200 µg/ml $279
p-β2-AR (Tyr 141) P sc-17275 P
(peptide)
 100 µg/0.5 ml $61
p-β2-AR Antibody (Tyr 141)-R sc-17275-R 200 µg/ml $279
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
β2-AR siRNA (h) sc-39866 10 µM $258
β2-AR siRNA (m) sc-39867 10 µM $258
β2-AR (h)-PR sc-39866-PR 10 µM, 20 µl $23
β2-AR (m)-PR sc-39867-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
β2-AR shRNA Plasmid (h) sc-39866-SH 20 µg $520
β2-AR shRNA Plasmid (m) sc-39867-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
β2-AR shRNA (h) Lentiviral Particles sc-39866-V 200 µl $625
β2-AR shRNA (m) Lentiviral Particles sc-39867-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HeLa + PMA Cell Lysate sc-2258 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ADRB2 154 5q33.1 NM_000024 P07550
 601665
Mouse Adrb2 11555 18 E1 P18762
 N/A
 

∫2 adrenergic receptors (∫2-ARs) bind catecholamines (epinephrine and norepinephrine) and influence development, behavior, cardiac function, smooth muscle tone, and metabolism. ∫2-AR signaling complexes can contain class C L-type calcium channel CaV1.2, G protein, adenylyl cyclase, cAMP-dependent kinase and PP2A phosphatase. ∫2-ARs are present in adipose, blood, lung, brain, heart, nose, pancreas, skeletal muscle, skin and vessels. Phosphorylation of Ser 345/346 and Ser 355/356 by PKA and GRK, respectively, promotes desensitization of the ∫2-AR.

p-β2-AR Antibody (Tyr 141) Data
Click on image to enlarge
sc-17275
p-β2-AR (Tyr 141)-R: sc-17275-R. Western blot analysis of β2-AR phosphorylation in PMA treated (A) and PMA and lambda protein phosphatase treated (B) HeLa whole cell lysates.
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