Welcome to Santa Cruz Biotechnology!
SCBT Home
Home » Structural Proteins » c-Cbl Associated Protein Antibodies » CAP2 Antibody (C-14): sc-167378

CAP2 Antibody (C-14): sc-167378

 |  Datasheet

(Based on data analysis)
  • CAP2 Antibody (C-14) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the C-terminus of CAP2 of human origin
  • recommended for detection of CAP2 of mouse, rat and human origin by WB, IF and ELISA; non cross-reactive with CAP1; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-167378 P
 

See additional c-Cbl Associated Protein Antibodies including c-Cbl Associated Protein, CAP and CAP2.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
CAP2 Antibody (C-14) sc-167378 200 µg/ml $279
CAP2 (C-14) P sc-167378 P
(peptide)
 100 µg/0.5 ml $61
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CAP2 10486 6p22.3 NM_006366 P40123
 n/a
Mouse Cap2 67252 13 A5 NM_026056 Q9CYT6
 N/A
 

Cyclase-associated proteins (CAPs) are a family of evolutionary conserved proteins that participate in signal transduction and function to regulate events associated with the actin cytoskeleton. CAP1 and CAP2 (adenylate cyclase-associated protein 1 and 2, respectively) are two members of the CAP family, both of which localize to the cell membrane and contain one C-CAP/cofactor C-like domain. CAP1 is involved in the regulation of actin filaments and is thought to mediate processes such as establishment of cell polarity and mRNA localization, while CAP2 has a bifunctional regulatory role and can interact directly with actin. Although CAP1 is expressed throughout the body, CAP2 is predominately expressed in skin, brain, heart and skeletal muscle. Overexpression of CAP2 is associated with hepatocellular carcinoma, suggesting a possible role for CAP2 in carcinogenesis.