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p-Na+/K+-ATPase α Antibody (Ser 23): sc-16711

 |  Datasheet

(Based on data analysis)
  • p-Na+/K+-ATPase α Antibody (Ser 23) is a goat polyclonal IgG provided at 200 µg/ml; also available as rabbit IgG provided at 200 µg/ml, sc-16711-R
  • epitope corresponding to a short amino acid sequence containing phosphorylated Ser 23 of sodium/potassium ATPase alpha of rat origin
  • recommended for detection of Ser 23 phosphorylated sodium/ potassium ATPase alpha of rat origin by WB, IF and ELISA
  • blocking peptide, sc-16711 P
 

See additional Sodium/Potassium-ATPase Protein Antibodies including Sodium/Potassium-ATPase Protein, H+/K+ ATPase beta, Na+/K+-ATPase alpha, Na+/K+-ATPase alpha 1, Na+/K+-ATPase alpha 4, Na+/K+-ATPase beta 1, Na+/K+-ATPase β2, Na+/K+-ATPase alpha 2, Na+/K+-ATPase beta 3 and Na+/K+ ATPase beta 4.

Ordering Information
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-Na+/K+-ATPase α Antibody (Ser 23) sc-16711 200 µg/ml $279
p-Na+/K+-ATPase α (Ser 23) P sc-16711 P
(peptide)
 100 µg/0.5 ml $61
p-Na+/K+-ATPase α Antibody (Ser 23)-R sc-16711-R 200 µg/ml $279

The ubiquitously expressed sodium/potassium-ATPase exists as a oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, sodium/potassium-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, å, ∫ and ©, comprise to form the sodium/potassium-ATPase oligomer. The å-subunit contains the binding sites for ATP and the cations. The glycosylated ∫-subunit ensures correct folding and membrane insertion of the å-subunits. The small ©-subunit colocalizes with the å-subunit in nephron segments where it increases the affinity of sodium/potassium ATPase for ATP. The ∫-subunit, but not the ©-subunit, is essential for normal activity of sodium/potassium ATPase.