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home » Channel Proteins » Sodium/Potassium-ATPase Protein Antibody / Sodium/Potassium-ATPase Protein Antibodies » p-Na+/K+-ATPase α (Ser 943): sc-16710

p-Na+/K+-ATPase α (Ser 943) Antibody: sc-16710

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml; also available as rabbit IgG, 200 µg/ml, sc-16710-R
  • epitope corresponding to a short amino acid sequence containing phosphorylated Ser 943 of sodium/potassium ATPase alpha of human origin
  • recommended for detection of Ser 943 phosphorylated sodium/ potassium ATPase alpha of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-16710 P
 
Additional Sodium/Potassium-ATPase Protein Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
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WB   IF  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ATP1A1 476 1p13.1 NM_000701, NM_001001586 P05023
 182310
Mouse Atp1a1 11928 3 F2.2 Q8VDN2
 N/A
Mouse Atp1a2 98660 1 H3 Q6PIE5
 N/A
Mouse Atp1a3 232975 7 A3 Q6PIC6
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
p-Na+/K+-ATPase α (Ser 943) sc-16710 200 µg/ml $279
p-Na+/K+-ATPase α (Ser 943) P sc-16710 P
(peptide)
 100 µg/0.5 ml $61
p-Na+/K+-ATPase α (Ser 943)-R sc-16710-R 200 µg/ml $279

Na+/K+-ATPase α Background Information
The ubiquitously expressed sodium/potassium-ATPase exists as a oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, sodium/potassium-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, å, ∫ and ©, comprise to form the sodium/potassium-ATPase oligomer. The å-subunit contains the binding sites for ATP and the cations. The glycosylated ∫-subunit ensures correct folding and membrane insertion of the å-subunits. The small ©-subunit colocalizes with the å-subunit in nephron segments where it increases the affinity of sodium/potassium ATPase for ATP. The ∫-subunit, but not the ©-subunit, is essential for normal activity of sodium/potassium ATPase.

p-Na+/K+-ATPase α (Ser 943) Product Citations
See how others have used p-Na+/K+-ATPase α (Ser 943): sc-16710 antibody and or p-Na+/K+-ATPase α (Ser 943) antibody conjugates.


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