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home » Kinases and Phosphatases » FAK Antibody / FAK Antibodies » p-FAK (Ser 722): sc-16662

p-FAK (Ser 722) Antibody: sc-16662

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml; also available as rabbit IgG, 200 µg/ml, sc-16662-R
  • epitope corresponding to a short amino acid sequence containing phosphorylated Ser 722 of focal adhesion kinase (FAK) of human origin
  • recommended for detection of Ser 722 phosphorylated FAK of mouse, rat and human origin by WB, IP and IF; also reactive with additional species, including equine, canine, bovine and avian
  • blocking peptide, sc-16662 P
 
Additional FAK Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PTK2 5747 8q24.3 NM_005607, NM_153831 Q05397
 600758
Mouse Ptk2 14083 15 D3 P34152
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
p-FAK (Ser 722) sc-16662 200 µg/ml $279
p-FAK (Ser 722) P sc-16662 P
(peptide)
 100 µg/0.5 ml $61
p-FAK (Ser 722)-R sc-16662-R 200 µg/ml $279
Lambda Phosphatase sc-200312 100,000 units $462
Lambda Phosphatase sc-200312A 20,000 units $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
FAK siRNA (h) sc-29310 10 µM $258
FAK siRNA (m) sc-35353 10 µM $258
FAK (h)-PR sc-29310-PR 10 µM $23
FAK (m)-PR sc-35353-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
FAK shRNA Plasmid (h) sc-29310-SH 20 µg $520
FAK shRNA Plasmid (m) sc-35353-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
FAK shRNA (h) Lentiviral Particles sc-29310-V 200 µl $625
FAK shRNA (m) Lentiviral Particles sc-35353-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NIH/3T3 + anisomycin Cell Lysate sc-2247 500 µg/200 µl $104
HeLa + serum Cell Lysate sc-24691 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
Hep G2 Cell Lysate sc-2227 500 µg/200 µl $104

FAK Background Information
Activation of integrins in the extracellular matrix (ECM) of eukaryotic cells promotes the formation of membrane adhesion complexes, known as focal adhesions, which can include cytoskeletal proteins and protein tyrosine kinases, such as focal adhesion kinase (FAK). Phosphorylation events occurring within focal adhesions influence numerous processes that include mitogenic signaling, cell survival and cell motility. FAK is a non-receptor tyrosine kinase that is ubiquitously expressed and highly conserved between species. FAK is recruited by integrin clusters and variably phosphorylated depending on the effector molecules present in the focal adhesion. Phospho-rylation of FAK Tyr 397 decreases during serum starvation, contact inhibition and cell cycle arrest, all conditions under which activating FAK Tyr 407 phosphorylation increases.

p-FAK (Ser 722) Product Citations
See how others have used p-FAK (Ser 722): sc-16662 antibody and or p-FAK (Ser 722) antibody conjugates.


4 total citations
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p-FAK (Ser 722)
Click on image to enlarge
sc-16662
Western blot analysis of FAK phosphorylation in NIH/3T3 cells treated with anisomycin. Blots were probed with FAK (C-20): sc-558 (A), p-FAK (Ser 722)-R: sc-16662-R preincubated with its cognate phosphorylated peptide (B) and p-FAK (Ser 722)-R: sc-16662-R preincubated with its cognate non-phosphorylated peptide (C).
sc-16662
p-FAK (Ser 722): sc-16662. Western blot analysis of FAK phosphorylation in 293T whole cell lysate.
sc-16662
p-FAK (Ser 722)-R: sc-16662-R. Western blot analysis of FAK phosphorylation in non-transfected 293T: sc-117752 (A), human FAK transfected 293T: sc-171032 (B) and HeLa (C) whole cell lysates.
sc-16662
Western blot analysis of FAK phosphorylation in non-transfected: sc-117752 (A,D), untreated human FAK transfected: sc-114600 (B,E) and lambda protein phosphatase treated human FAK transfected: sc-114600 (C,F) 293T whole cell lysates. Antibodies tested include p-FAK (Ser 722)-R: sc-16662-R (A,B,C) and FAK (C-903): sc-932 (D,E,F).
sc-16662
Western blot analysis of FAK phosphorylation in non-transfected: sc-117752 (A,D), untreated human FAK transfected: sc-114600 (B,E) and lambda protein phosphatase (sc-200312A) treated human FAK transfected: sc-114600 (C,F) 293T whole cell lysates. Antibodies tested include p-FAK (Ser 722)-R: sc-16662-R (A,B,C) and FAK (C-903): sc-932 (D,E,F).
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