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ALDH1/2 Antibody (H-8): sc-166362


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  • ALDH1/2 Antibody (H-8) is a mouse monoclonal IgG2b (kappa light chain) provided at 200 µg/ml
  • raised against amino acids 186-270 mapping within an internal region of ALDH1A1 of human origin
  • recommended for detection of ALDH1A1, ALDH1A2, ALDH1A3 and ALDH2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
  • agarose (sc-166362 AC), 500 µg/0.25 ml agarose in 1 ml, for IP; HRP (sc-166362 HRP), 200 µg/ml, for WB, IHC(P) and ELISA; phycoerythrin (sc-166362 PE), fluorescein (sc-166362 FITC), Alexa Fluor® 488 (sc-166362 AF488) or Alexa Fluor® 647 (sc-166362 AF647), 200 µg/ml, for IF, IHC(P) and FCM
  • See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP): sc-516102, m-IgGκ BP-FITC: sc-516140, m-IgGκ BP-PE: sc-516141, or m-IgGκ BP-B: sc-516142, our highly recommended recombinant alternatives to conventional secondary anti-mouse IgG reagents.
  • See 3 citations for ALDH1/2 Antibody (H-8)
Full-length ALDH1/2 protein sequence with immunogen highlighted:

See additional ALDH Antibodies including ALDH, ALDH1, ALDH1A7, ALDH2, ALDH1A1, ALDH1B1, ALDH1L1, ALDH1A2, ALDH1L2, ALDH1A3, ALDH3A1, ALDH3B1, ALDH3A2, ALDH3B2, ALDH4A1, ALDH5A1, ALDH6A1, ALDH8A1, ALDH9A1, ALDH16A1 and ALDH18A1.

Also see chemical ALDH1 Inhibitors or chemical ALDH2 Inhibitors for functional analysis of cellular responses to ALDH1 and ALDH2.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
ALDH1/2 Antibody (H-8) sc-166362 200 µg/ml $279
ALDH1/2 Antibody (H-8) AC sc-166362 AC 500 µg/ml, 25% ag $366
ALDH1/2 Antibody (H-8) AF488 sc-166362 AF488 200 µg/ml $314
ALDH1/2 Antibody (H-8) AF647 sc-166362 AF647 200 µg/ml $314
ALDH1/2 Antibody (H-8) FITC sc-166362 FITC 200 µg/ml $292
ALDH1/2 Antibody (H-8) HRP sc-166362 HRP 200 µg/ml $279
ALDH1/2 Antibody (H-8) PE sc-166362 PE 200 µg/ml $303
 CRISPR KO, HDR and Nickase Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ALDH2 CRISPR/Cas9 KO Plasmid (h) sc-400809 20 µg $345
ALDH2 HDR Plasmid (h) sc-400809-HDR 20 µg $385
ALDH2 Double Nickase Plasmid (h) sc-400809-NIC 20 µg $355
ALDH2 Double Nickase Plasmid (h2) sc-400809-NIC-2 20 µg $355
ALDH2 CRISPR/Cas9 KO Plasmid (m) sc-419079 20 µg $345
ALDH2 HDR Plasmid (m) sc-419079-HDR 20 µg $385
ALDH2 Double Nickase Plasmid (m) sc-419079-NIC 20 µg $355
ALDH2 Double Nickase Plasmid (m2) sc-419079-NIC-2 20 µg $355
 CRISPR Activation Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ALDH2 CRISPR Activation Plasmid (h) sc-400809-ACT 20 µg $345
ALDH2 CRISPR Activation Plasmid (h2) sc-400809-ACT-2 20 µg $345
ALDH2 Lentiviral Activation Particles (h) sc-400809-LAC 200 µl $395
ALDH2 Lentiviral Activation Particles (h2) sc-400809-LAC-2 200 µl $395
ALDH2 CRISPR Activation Plasmid (m) sc-419079-ACT 20 µg $345
ALDH2 CRISPR Activation Plasmid (m2) sc-419079-ACT-2 20 µg $345
ALDH2 Lentiviral Activation Particles (m) sc-419079-LAC 200 µl $395
ALDH2 Lentiviral Activation Particles (m2) sc-419079-LAC-2 200 µl $395
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Hep G2 Cell Lysate sc-2227 500 µg/200 µl $104
mouse liver extract sc-2256 500 µg/200 µl $104
rat liver extract sc-2395 500 µg/200 µl $104
ALDH1A1 (m): 293T Lysate sc-118332 100 µg/200 µl $205
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ALDH1A1 216 9q21.13 NM_000689 P00352
Human ALDH2 217 12q24.12 NM_000690, NM_001204889 P05091
Human ALDH1A3 220 15q26.3 NM_000693 P47895
Human ALDH1A2 8854 15q21.3 NM_001206897, NM_003888, NM_170696, NM_170697 O94788
Mouse Aldh1a1 11668 19 B NM_013467 P24549
Mouse Aldh2 11669 5 F NM_009656 P47738
Mouse Aldh1a2 19378 9 D NM_009022 Q62148
Mouse Aldh1a3 56847 7 C NM_053080 Q9JHW9

Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1); aldehyde dehydrogenase family 1 member A1; aldehyde dehydrogenase cytosolic; ALDHII; ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). The major liver isoform ALDH1 localizes to cytosolic space, while ALDH2 localizzes to the mitochondria. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH2 is present in most Caucasians, yet is absent in 50% of Asians. The absence of this enzyme has been linked to alcohol intolerance; and thusly, a reduced risk for alcoholism-related liver disease.

ALDH1/2 Antibody (H-8) Product Reviews

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ALDH1/2 Antibody (H-8) Product Citations
See how others have used ALDH1/2 Antibody (H-8) and or ALDH1/2 Antibody (H-8) conjugates.

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ALDH1/2 Antibody (H-8) Data
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ALDH1/2 (H-8): sc-166362. Western blot analysis of ALDH1/2 expression in rat liver tissue extract.
ALDH1/2 (H-8): sc-166362. Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining of cells in tubules.
ALDH1/2 (H-8): sc-166362. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
ALDH1/2 (H-8): sc-166362. Western blot analysis of ALDH1/2 expression in Hep G2 (A), A549 (B) and Caki-1 (C) whole cell lysates and mouse liver tissue extract (D).
ALDH1/2 (H-8): sc-166362. Western blot analysis of ALDH1/2 expression in human skeletal muscle tissue extract.
ALDH1/2 (H-8): sc-166362. Western blot analysis of ALDH1A1 expression in non-transfected 293T: sc-117752 (A), mouse ALDH1A1 transfected 293T: sc-118332 (B) and Hep G2 (C) whole cell lysates.
ALDH1/2 (H-8): sc-166362. Western blot analysis of ALDH2 expression in non-transfected: sc-110760 (A) and human ALDH2 transfected: sc-158255 (B) 293 whole cell lysates.