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Heme Oxygenase 2/3 Antibody (B-4): sc-166299

 |  Datasheet

(Based on data analysis)

  • Heme Oxygenase 2/3 Antibody (B-4) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against amino acids 1-300 mapping at the N-terminus of Heme Oxygenase 2 of mouse origin
  • recommended for detection of Heme Oxygenase 2 of m, r and h origin, Heme Oxygenase 3 of m and r origin, and, to a lesser extent, Heme Oxygenase 1 of mouse and human origin by WB, IP, IF and ELISA
 
Full-length Heme Oxygenase 2/3 protein sequence with immunogen highlighted:
MSSEVETSEGVDESEKNSMAPEKENHTKMADLSELLKEGTKEAHDRAENTQFVKDFLKGNIKKELFKLATTALYFTYSALEEEMDRNKDHPAFAPLYFPTELHRKAALIKDMKYFFGENWEEQVKCSEAAQKYVDRIHYVGQNEPELLVAHAYTRYMGDLSGGQVLKKVAQRALKLPSTGEGTQFYLFEHVDNAQQFKQFYRARMNALDLNLKTKERIVEEANKAFEYNMQIFSELDQAGSMLARETLEDGLPVHDGKGDIRKCPFYAAQPDKGTLGGSNCPFQTTVAVLRKPSLQLILASVALVAGLLAWYYM

See additional Heme Oxygenase Antibodies including Heme Oxygenase, Heme Oxygenase 1, Heme Oxygenase 2 and Heme Oxygenase 3.

Also see Heme Oxygenase Inhibitors for functional analysis of cellular responses to Heme Oxygenase.


Ordering InformationGene Info
Recommended Support Products:
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WB   IP   IF  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Heme Oxygenase 2/3 Antibody (B-4) sc-166299 200 µg/ml $279
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Heme Oxygenase 2 (h2): 293T Lysate sc-177338 100 µg/200 µl $205
RAW 264.7 Whole Cell Lysate sc-2211 500 µg/200 µl $104
NIH/3T3 + heat shock Cell Lysate sc-2217 500 µg/200 µl $104
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
ECV304 Cell Lysate sc-2269 500 µg/200 µl $104
rat spleen extract sc-2397 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
Heme Oxygenase 2 (m): 293T Lysate sc-120746 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human HMOX2 3163 16p13.3 P30519
 141251
Mouse Hmox2 15369 16 A1 O70252
 N/A
 

Heme oxygenases are microsomal enzymes that cleave heme to produce the antioxidant biliverdin, inorganic iron and carbon monoxide (CO). The activity of Heme Oxygenase 1 (HO-1), also designated HSP 32, is highly inducible in response to numerous stimuli, including heme, heavy metals, hormones and oxidative stress. Heme Oxygenase 2, in contrast, appears to be constituitively expressed in mammalian tissues. Heme Oxygenase 2 is involved in the production of carbon monoxide (CO) in brain, where CO is thought to act as a neurotransmitter. The CO signaling system closely parallels the signaling pathway involving nitric oxide, and regulation of the two systems is closely linked. Heme Oxygenase 3 is found in the spleen, liver, thymus, prostate, heart, kidney, brain and testis. A poor heme catalyst, Heme Oxygenase 3 has two heme regulatory motifs that may be involved in heme binding.

Heme Oxygenase 2/3 Antibody (B-4) Data
Click on image to enlarge
sc-166299
Heme Oxygenase 2/3 (B-4): sc-166299. Western blot analysis of Heme Oxygenase 2 expression in non-transfected 293T: sc-117752 (A), mouse Heme Oxygenase 2 transfected 293T: sc-120746 (B), NIH/3T3 (C) and K-562 (D) whole cell lysates.
sc-166299
Heme Oxygenase 2/3 (B-4): sc-166299. Western blot analysis of Heme Oxygenase 2 expression in non-transfected: sc-117752 (A) and human Heme Oxygenase 2 transfected: sc-177338 (B) 293T whole cell lysates.
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