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GlnRS Antibody (F-4): sc-166241

 |  Datasheet

(Based on data analysis)

  • GlnRS Antibody (F-4) is a mouse monoclonal IgG2b provided at 200 µg/ml
  • raised against amino acids 513-775 mapping at the C-terminus of GlnRS of human origin
  • recommended for detection of GlnRS of human origin by WB, IP, IF, IHC(P) and ELISA
 
Full-length GlnRS protein sequence with immunogen highlighted:
MAALDSLSLFTSLGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLASRLRDTRRLSFLVSYIASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPEQIEEAVEAAINRHRPQLLVERYHFNMGLLMGEARAVLKWADGKMIKNEVDMQVLHLLGPKLEADLEKKFKVAKARLEETDRRTAKDVVENGETADQTLSLMEQLRGEALKFHKPGENYKTPGYVVTPHTMNLLKQHLEITGGQVRTRFPPEPNGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGYTPYKVTYASDYFDQLYAWAVELIRRGLAYVCHQRGEELKGHNTLPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVMEDGKMDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVYCPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTMEPHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIERTDFKEEPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVESLEVTCRRADAGEKPKAFIHWVSQPLMCEVRLYERLFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVALAKPFDKFQFERLGYFSVDPDSHQGKLVFNRTVTLKEDPGKV

See additional GlnRS Antibodies.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
GlnRS Antibody (F-4) sc-166241 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
GlnRS siRNA (h) sc-75144 10 µM $258
GlnRS siRNA (m) sc-75145 10 µM $258
GlnRS (h)-PR sc-75144-PR 10 µM, 20 µl $23
GlnRS (m)-PR sc-75145-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
GlnRS shRNA Plasmid (h) sc-75144-SH 20 µg $520
GlnRS shRNA Plasmid (m) sc-75145-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
GlnRS shRNA (h) Lentiviral Particles sc-75144-V 200 µl $625
GlnRS shRNA (m) Lentiviral Particles sc-75145-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
GlnRS (h3): 293T Lysate sc-113657 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human QARS 5859 3p21.31 P47897
 603727
Mouse Qars 97541 9 F2 NP_598555
 N/A
 

Aminoacyl-tRNA synthetases function to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide triplets. GlnRS (Glutaminyl-tRNA synthetase), also known as QARS, is a 775 amino acid member of the class-I aminoacyl-tRNA synthetase family. Localized to the cytoplasm, GlnRS is part of a multi-protein complex composed of nine aminoacyl-tRNA synthetases that are specific for nine amino acids, namely Arg, Asp, Glu, Gln, Ile, Leu, Lys, Met and Pro. In this complex, GlnRS functions to catalyze the ATP-dependent conversion of L-glutamine (Gln) and tRNA(Gln) to Gln-tRNA(Gln). While GlnRS is used to synthesize Gln-tRNA(Gln) in many eukaryotic cells, prokaryotes and organelles, such as mitochondria and chloroplasts, can synthesize Gln-tRNA(Gln) in a two step process involving misacylation and amidation reactions.

GlnRS Antibody (F-4) Data
Click on image to enlarge
sc-166241
GlnRS (F-4): sc-166241. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
sc-166241
GlnRS (F-4): sc-166241. Western blot analysis of GlnRS expression in non-transfected 293T: sc-117752 (A), human GlnRS transfected 293T: sc-113657 (B) and HeLa (C) whole cell lysates.
sc-166241
GlnRS (F-4): sc-166241. Immunoperoxidase staining of formalin fixed, paraffin-embedded human brain tissue showing cytoplasmic staining of neuronal and glial cells.
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