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PACAP (F-2) Antibody: sc-166180

 |  Datasheet
  • mouse monoclonal IgM, 200µg/ml
  • raised against amino acids 101-176 of PACAP of human origin
  • recommended for detection of PACAP and, to a lesser extent, VIP of human and rat origin by WB, IP, IF and ELISA
 
Additional PACAP Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ADCYAP1 116 18p11.32 P18509
102980
Mouse Adcyap1 11516 17 E5 O70176
N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
PACAP (F-2) sc-166180 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PACAP siRNA (h) sc-39530 10 µM $258
PACAP siRNA (m) sc-39531 10 µM $258
PACAP (h)-PR sc-39530-PR 10 µM $23
PACAP (m)-PR sc-39531-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PACAP shRNA Plasmid (h) sc-39530-SH 20 µg $520
PACAP shRNA Plasmid (m) sc-39531-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
PACAP shRNA (h) Lentiviral Particles sc-39530-V 200 µl $625
PACAP shRNA (m) Lentiviral Particles sc-39531-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
rat testis extract sc-2400 500 µg/200 µl $104

PACAP Background Information
Glucagon is a pancreatic hormone that functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels (1). Glucagon-like peptide-1 (GLP-1), Glucagon-like peptide-2 (GLP-2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are members of the glucagon family of hormones (2). GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior, whereas GLP-2 is a stimulator of intestinal epithelial growth (3,4). VIP causes vasodilation resulting in the lowering of blood pressure (5). PACAP is abundant in the hypothalamus and has been shown to increase the synthesis of several hormones, including growth hormone (6).

PACAP (F-2)
Click on image to enlarge
PACAP (F-2): sc-166180. Western blot analysis of PACAP expression in rat testis tissue extract.
PACAP (F-2): sc-166180. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
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