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- mouse monoclonal IgG1, 200µg/ml
- raised against amino acids 331-476 mapping at the C-terminus of DCDC2 of human origin
- recommended for detection of all DCDC2 human isoforms of human origin by WB, IP, IF and ELISA
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Ordering Information
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
DCDC2 |
51473 |
6p22.2 |
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Q9UHG0
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605755 |
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DCDC2 Background Information
The DCDC2 gene encodes the DCDC2 protein (Doublecortin-containing protein 2, RU2, RU2S) which contains two Doublecortin peptide domains similar to those in the Doublecortin gene. DCDC2 is transcribed as a “normal” gene, which results in a sense transcript (RU2S), but when it is transcribed in the opposite direction, a shorter antisense transcript (RU2AS), which is found in tumors, results. The DCDC2 protein demonstrates ubiquitous expression, whereas RU2AS expression is restricted to normal kidney, bladder, liver and testis, and to tumors of various histologic origins. The deduced DCDC2 protein contains 476 amino acids, while the RU2AS protein contains 84 residues. There is a significant association between dyslexia and several SNPs within the DCDC2 gene.
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DCDC2 (C-4)
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DCDC2 (C-4): sc-166051. Western blot analysis of DCDC2 expression in non-transfected: sc-117752 (A) and human DCDC2 transfected: sc-116299 (B) 293T whole cell lysates. |
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