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Fibrillarin Antibody (G-4): sc-166021

 |  Datasheet

(Based on data analysis)

  • Fibrillarin Antibody (G-4) is a mouse monoclonal IgG2b provided at 200 µg/ml
  • raised against amino acids 61-200 of Fibrillarin of human origin
  • recommended for detection of Fibrillarin of mouse and human origin by WB, IP, IF, IHC(P) and ELISA
 
Full-length Fibrillarin protein sequence with immunogen highlighted:
MKPGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGGNRGRGRGGKRGNQSGKNVMVEPHRHEGVFICRGKEDALVTKNLVPGESVYGEKRVSISEGDDKIEYRAWNPFRSKLAAAILGGVDQIHIKPGAKVLYLGAASGTTVSHVSDIVGPDGLVYAVEFSHRSGRDLINLAKKRTNIIPVIEDARHPHKYRMLIAMVDVIFADVAQPDQTRIVALNAHTFLRNGGHFVISIKANCIDSTASAEAVFASEVKKMQQENMKPQEQLTLEPYERDHAVVVGVYRPPPKVKN

See additional Fibrillarin Antibodies.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Fibrillarin Antibody (G-4) sc-166021 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Fibrillarin siRNA (h) sc-37883 10 µM $258
Fibrillarin siRNA (m) sc-37884 10 µM $258
Fibrillarin (h)-PR sc-37883-PR 10 µM, 20 µl $23
Fibrillarin (m)-PR sc-37884-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Fibrillarin shRNA Plasmid (h) sc-37883-SH 20 µg $520
Fibrillarin shRNA Plasmid (m) sc-37884-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Fibrillarin shRNA (h) Lentiviral Particles sc-37883-V 200 µl $625
Fibrillarin shRNA (m) Lentiviral Particles sc-37884-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
Hep G2 Cell Lysate sc-2227 500 µg/200 µl $104
MOLT-4 nuclear extract sc-2151 250 µg/0.05 ml $143
K-562 nuclear extract sc-2130 250 µg/0.05 ml $143
rat liver extract sc-2395 500 µg/200 µl $104
Fibrillarin (m): 293T Lysate sc-126852 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human FBL 2091 19q13.2 P22087
134795
Mouse Fbl 14113 7 A3 P35550
N/A
 


Fibrillarin is a widely occurring, basic, nonhistone protein that is localized exclusively in the fibrillar region of the nucleolus, including both the dense fibrillar and the fibrillar center regions. Fibrillarin is also expressed in HeLa cells, 3T3 cells, and human peripheral blood lymphocytes. In metaphase and anaphase, fibrillarin is found on putative chromosomal nucleolar regions (NORs). During telophase, fibrillarin is an early marker for the site of the newly forming nucleolus. The structure of fibrillarin includes an RNA-binding domain and an RNP consensus sequence, which is consistent with the association of fibrillarin with the U3 small nucleolar RNA. Fibrillarin is involved in processing rRNA transcripts in the nucleolus.

Fibrillarin Antibody (G-4) Data
Click on image to enlarge
Fibrillarin (G-4): sc-166021. Western blot analysis of Fibrillarin expression in non-transfected: sc-117752 (A) and mouse Fibrillarin transfected: sc-126852 (B) 293T whole cell lysates.
Fibrillarin (G-4): sc-166021. Western blot analysis of Fibrillarin expression in Hep G2 whole cell lysate.
Fibrillarin (G-4): sc-166021. Immunofluorescence staining of formalin-fixed Hep G2 cells showing nucleolar localization.
Fibrillarin (G-4): sc-166021. Immunoperoxidase staining of formalin fixed, paraffin-embedded human breast tissue showing nuclear staining of glandular cells.
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