santa cruz biotechnology, inc.
SCBT Logo

Welcome!        Items in Cart     Quick Order
home » Synthesis and Degradation » ADAM Antibody / ADAM Antibodies » ADAM10 (A-20): sc-16524

ADAM10 (A-20) Antibody: sc-16524

  |  Datasheet
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping within an internal region of ADAM10 of human origin
  • recommended for detection of ADAM10 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-16524 P
 
Additional ADAM Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ADAM10 102 15q22.1 NM_001110 O14672
 602192
Mouse Adam10 11487 9 D O35598
 N/A
 
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
ADAM10 (A-20) sc-16524 200 µg/ml $279
ADAM10 (A-20) P sc-16524 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ADAM10 siRNA (h) sc-41410 10 µM $258
ADAM10 siRNA (m) sc-41411 10 µM $258
ADAM10 (h)-PR sc-41410-PR 10 µM $23
ADAM10 (m)-PR sc-41411-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ADAM10 shRNA Plasmid (h) sc-41410-SH 20 µg $520
ADAM10 shRNA Plasmid (m) sc-41411-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
ADAM10 shRNA (h) Lentiviral Particles sc-41410-V 200 µl $625
ADAM10 shRNA (m) Lentiviral Particles sc-41411-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
3T3-L1 Cell Lysate sc-2243 500 µg/200 µl $104
NIH/3T3 Whole Cell Lysate sc-2210 500 µg/200 µl $104
U-937 Cell Lysate sc-2239 500 µg/200 µl $104
HuT 78 Whole Cell Lysate sc-2208 500 µg/200 µl $104
KNRK Whole Cell Lysate sc-2214 500 µg/200 µl $104
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
PC-12 Cell Lysate sc-2250 500 µg/200 µl $104

ADAM10 Background Information
ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in cell-cell, cell-matrix interface related processes including fertilization, muscle fusion, secretion of TNFå (tumor necrosis factor å), and modulation of the neurogenic function of Notch and Delta. ADAM proteins possess a signal-domain, a pro-domain, a metalloprotease domain, a disintegrin domain (integrin ligand) a cysteine-rich region, an epidermal growth factor-like domain, a transmembrane domain and a cytoplasmic tail. ADAMs are expressed in brain, testis, epididymis, ovary, breast, placenta, liver, heart, lung, bone and muscle, and catalyze proteolysis, adhesion, fusion and intracellular signaling. ADAM10 is a TNF-processing enzyme that cleaves pro-TNF, a membrane-bound precusor protein, at Ala 76-Val 77, which causes membrane shedding of soluble TNF.
ADAM10 (A-20)
Click on image to enlarge
sc-16524
ADAM10 (A-20): sc-16524. Western blot analysis of ADAM10 expression in MH-S (A), 3T3-L1 (B), NIH/3T3 (C) and U-937 (D) whole cell lysates.
Download
Datasheets
Get Adobe Acrobat Reader