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CLC-4 Antibody (C-20): sc-16435

 |  Datasheet

(Based on data analysis)
  • CLC-4 Antibody (C-20) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the C-terminus of CLC-4 of human origin
  • recommended for detection of CLC-4 of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
  • blocking peptide, sc-16345 P
  • See 1 citations for CLC-4 Antibody (C-20)
 

See additional CLC Antibodies including CLC, CLC-1, CLC-3 4 5, CLC-K, CLC-KA, CLC-KB, CLC-2, CLC-3, CLC-4, CLC-5, CLC-6 and CLC-7.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
CLC-4 Antibody (C-20) sc-16435 200 µg/ml $279
CLC-4 (C-20) P sc-16435 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CLC-4 siRNA (h) sc-42383 10 µM $258
CLC-4 siRNA (m) sc-42384 10 µM $258
CLC-4 (h)-PR sc-42383-PR 10 µM, 20 µl $23
CLC-4 (m)-PR sc-42384-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CLC-4 shRNA Plasmid (h) sc-42383-SH 20 µg $520
CLC-4 shRNA Plasmid (m) sc-42384-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
CLC-4 shRNA (h) Lentiviral Particles sc-42383-V 200 µl $625
CLC-4 shRNA (m) Lentiviral Particles sc-42384-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CLCN4 1183 Xp22.2 NM_001830 P51793
 302910
Mouse Clcn4-2 12727 7 A1 Q61418
 N/A
 

The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, 3q28, 4q32, Xp22.3, Xp11.23-p11.22, 1p36 and 16p13, respectively. CLC1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC2 is highly expressed in the epithelia of several organs including lung, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis. CLC3 expression is particularly abundant in neuronal tissue, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC5 lead to Dent’s disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.

CLC-4 Antibody (C-20) Product Citations
See how others have used CLC-4 Antibody (C-20) and or CLC-4 Antibody (C-20) conjugates.


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