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Myosin IIIa Antibody (D-14): sc-163105

 |  Datasheet

(Based on data analysis)
  • Myosin IIIa Antibody (D-14) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of Myosin IIIa of human origin
  • recommended for detection of Myosin IIIa of mouse, rat and human origin by WB, IF and ELISA; non cross-reactive with Myosin IIIb
  • blocking peptide, sc-163105 P
 

See additional Myosin Antibodies including Myosin, MYH, MYH1, MYH8, MYL, MYL1, MYL10, Mylc2b, Myosin Ia, Myosin Ib, Myosin Ic, Myosin Id, Myosin Ie, Myosin If, Myosin Ig, Myosin Ih, myosin IIa, Myosin IIIb, Myosin IXa, Myosin IXb, Myosin IXI, Myosin Va, Myosin Vb, Myosin Vc, Myosin VI, Myosin VIIa, Myosin VIIB, Myosin X, Myosin XIX, Myosin XVA, Myosin XVI, Myosin XVIIIa, Myosin XVIIIb, Myosin-neonatal, MRLC2, MYH2, MYL2, MRCL3, MYH3, MYL3, MYH4, MYL4, MYL5, MYH6, MYL6, MYL6B, MYH7, MYL7, MYH9, MYL9, MYH10, MYH11, MYH13, MYH14 and MYH15.

Also see Myosin Inhibitors for functional analysis of cellular responses to Myosin.


Ordering InformationGene Info
Recommended Support Products:
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Myosin IIIa Antibody (D-14) sc-163105 200 µg/ml $279
Myosin IIIa (D-14) P sc-163105 P
(peptide)
 100 µg/0.5 ml $61
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MYO3A 53904 10p12.1 NM_017433 Q8NEV4
 607101
Mouse Myo3a 667663 2 A3 NM_148413 Q8K3H5
 N/A
 

Myosins are highly conserved, ubiquitously expressed proteins that interact with Actin to generate the force for cellular movements. The human genome encodes over 40 different Myosin genes which are divided into distinct classes, the most notable of which are the conventional Myosins (class II) and the unconventional Myosins (classes I and III through XV). Myosin IIIA, also known as MYO3A or DFNB30, is a 1,616 amino acid class III Myosin that contains one protein kinase domain, one myosin head-like domain and three IQ domains. Highly expressed in pancreas, cochlea and retinal pigment cells, Myosin IIIA is thought to function as an Actin-based motor that may play a role in both vision and hearing. Additionally, via its protein kinase domain, Myosin IIIA is able to catalyze the ATP-dependent phosphorylation of a variety of target proteins. Defects in the gene encoding Myosin IIIA are the cause of non-syndromic sensorineural deafness autosomal recessive type 30 (DFNB30), a form of hearing loss that is caused by damage to neural receptors in the brain or inner ear.