 |
- rabbit polyclonal IgG, 200 µg/ml; also available as goat IgG, 200 µg/ml, sc-163-G
- epitope mapping at the C-terminus of Cdk2 of human origin
- recommended for detection of Cdk2 of mouse, rat, human and hamster origin by WB, IP, KA, IF and ELISA; also reactive with additional species, including cow
- blocking peptide, sc-163 P
- agarose conjugate for IP studies, sc-163 AC, 500 µg/0.25 ml agarose
- HRP conjugate, sc-163 HRP, 200 µg/ml
|
|
| |
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
Cdk2 Background Information In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclin-dependent kinase 2 (Cdk2) p33, also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2 p34-related cyclin dependent kinases have been identified. These include Cdk3-Cdk8, PCTAIRE-1-3 and KKIALRE.
| Cdk2 (M2) Product Citations |
See how others have used Cdk2 (M2): sc-163 antibody and or Cdk2 (M2) antibody conjugates.
602 total citations Loading citations.
|
| |
|
 |
|
Cdk2 (M2)
Click on image to enlarge
|
|
Cdk2 (M2): sc-163. Immunofluorescence staining of methanol-fixed SK-BR-3 cells showing nuclear localization.
Western blot analysis of Cdk2 expression in NAMALWA (A,F), A-431 (B), HeLa (C), MCF7 (D) and SK-BR-3 (E) whole cell lysates. Antibodies tested include Cdk2 (M2): sc-163 (A-E) and Cdk2 (M2)-G: sc-163-G (F).
Cdk2 siRNA (h): sc-29259. Western blot analysis of Cdk2 expression in non-transfected control (A) and Cdk2 siRNA transfected (B) HeLa cells. Blot probed with Cdk2 (M2): sc-163. Actin (I-19): sc-1616 used as specificity and loading control.
Cdk2 (M2): sc-163. Western blot analysis of Cdk2 expression in non-transfected: sc-117752 (A) and mouse Cdk2 transfected: sc-119146 (B) 293T whole cell lysates.
Cdk2 (M2)-G: sc-163-G. Western blot analysis of Cdk2 expression in non-transfected: sc-117752 (A) and mouse Cdk2 transfected: sc-119146 (B) 293T whole cell lysates.
Cdk2 (M2): sc-163. Western blot analysis of Cdk2 expression in non-transfected 293T: sc-117752 (A), human Cdk2 transfected 293T: sc-172351 (B) and NAMALWA (C) whole cell lysates.
Cdk2 (M2)-G: sc-163-G. Western blot analysis of Cdk2 expression in non-transfected 293T: sc-117752 (A), human Cdk2 transfected 293T: sc-172351 (B) and NAMALWA (C) whole cell lysates.
Cdk2 (M2)-G: sc-163-G. Western blot analysis of Cdk2 expression in non-transfected: sc-117752 (A) and human Cdk2 transfected: sc-128295 (B) 293T whole cell lysates.
Cdk2 (M2): sc-163. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
|
|
Download
|
|