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Cdk2 (M2) Antibody: sc-163

 |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml; also available as goat IgG, 200 µg/ml, sc-163-G
  • epitope mapping at the C-terminus of Cdk2 of human origin
  • recommended for detection of Cdk2 of mouse, rat, human and hamster origin by WB, IP, KA, IF and ELISA; also reactive with additional species, including cow
  • blocking peptide, sc-163 P
  • agarose conjugate for IP studies, sc-163 AC, 500 µg/0.25 ml agarose
  • HRP conjugate, sc-163 HRP, 200 µg/ml
 
Additional CLK Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CDK2 1017 12q13.2 NM_001798, NM_052827 P24941
116953
Mouse Cdk2 12566 10 D3 P97377
N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Cdk2 (M2) sc-163 200 µg/ml $279
Cdk2 (M2) AC sc-163 AC 500µg/ml, 25%ag $366
Cdk2 (M2) HRP sc-163 HRP 200 µg/ml $279
Cdk2 (M2) P sc-163 P
(peptide)
100 µg/0.5 ml $61
Cdk2 (M2)-G sc-163-G 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdk2 siRNA (h) sc-29259 10 µM $258
Cdk2 siRNA (m) sc-29260 10 µM $258
Cdk2 siRNA (h2) sc-156139 200 µg/ml $258
Cdk2 (h)-PR sc-29259-PR 10 µM $23
Cdk2 (m)-PR sc-29260-PR 10 µM $23
Cdk2 (h2)-PR sc-156139-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdk2 shRNA Plasmid (h) sc-29259-SH 20 µg $520
Cdk2 shRNA Plasmid (m) sc-29260-SH 20 µg $520
Cdk2 shRNA Plasmid (h2) sc-156139-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdk2 shRNA (h) Lentiviral Particles sc-29259-V 200 µl $625
Cdk2 shRNA (m) Lentiviral Particles sc-29260-V 200 µl $625
Cdk2 shRNA (h2) Lentiviral Particles sc-156139-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
NAMALWA Cell Lysate sc-2234 500 µg/200 µl $104
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
MCF7 Whole Cell Lysate sc-2206 500 µg/200 µl $104
SK-BR-3 Cell Lysate sc-2218 500 µg/200 µl $104
K-562 Whole Cell Lysate sc-2203 500 µg/200 µl $104
HeLa nuclear extract sc-2120 1000 µg $143
 WB Control Recombinant Protein (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Cdk2 (1-298) sc-4069 50 µg $167

Cdk2 Background Information
In vertebrates, as in yeast, multiple cyclins have been identified, including a total of eight such regulatory proteins in mammals. In contrast to the situation in yeast, the Cdc2 p34 kinase is not the only catalytic subunit identified in vertebrates that can interact with cyclins. While Cdc2 p34 is essential for the G2 to M transition in vertebrate cells, a second Cdc2-related kinase has also been implicated in cell cycle control. This protein, designated cyclin-dependent kinase 2 (Cdk2) p33, also binds to cyclins and its kinase activity is temporally regulated during the cell cycle. Several additional Cdc2 p34-related cyclin dependent kinases have been identified. These include Cdk3-Cdk8, PCTAIRE-1-3 and KKIALRE.

Cdk2 (M2) Product Citations
See how others have used Cdk2 (M2): sc-163 antibody and or Cdk2 (M2) antibody conjugates.


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Cdk2 (M2)
Click on image to enlarge
Cdk2 (M2): sc-163. Immunofluorescence staining of methanol-fixed SK-BR-3 cells showing nuclear localization.
Western blot analysis of Cdk2 expression in NAMALWA (A,F), A-431 (B), HeLa (C), MCF7 (D) and SK-BR-3 (E) whole cell lysates. Antibodies tested include Cdk2 (M2): sc-163 (A-E) and Cdk2 (M2)-G: sc-163-G (F).
Cdk2 siRNA (h): sc-29259. Western blot analysis of Cdk2 expression in non-transfected control (A) and Cdk2 siRNA transfected (B) HeLa cells. Blot probed with Cdk2 (M2): sc-163. Actin (I-19): sc-1616 used as specificity and loading control.
Cdk2 (M2): sc-163. Western blot analysis of Cdk2 expression in non-transfected: sc-117752 (A) and mouse Cdk2 transfected: sc-119146 (B) 293T whole cell lysates.
Cdk2 (M2)-G: sc-163-G. Western blot analysis of Cdk2 expression in non-transfected: sc-117752 (A) and mouse Cdk2 transfected: sc-119146 (B) 293T whole cell lysates.
Cdk2 (M2): sc-163. Western blot analysis of Cdk2 expression in non-transfected 293T: sc-117752 (A), human Cdk2 transfected 293T: sc-172351 (B) and NAMALWA (C) whole cell lysates.
Cdk2 (M2)-G: sc-163-G. Western blot analysis of Cdk2 expression in non-transfected 293T: sc-117752 (A), human Cdk2 transfected 293T: sc-172351 (B) and NAMALWA (C) whole cell lysates.
Cdk2 (M2)-G: sc-163-G. Western blot analysis of Cdk2 expression in non-transfected: sc-117752 (A) and human Cdk2 transfected: sc-128295 (B) 293T whole cell lysates.
Cdk2 (M2): sc-163. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
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