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SLC5A12 Antibody (S-17): sc-162221

 |  Datasheet

(Based on data analysis)
  • SLC5A12 Antibody (S-17) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an extracellular domain of SLC5A12 of human origin
  • recommended for detection of SLC5A12 of mouse, rat and human origin by WB, IF and ELISA; non cross-reactive with SLC5A8; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-162221 P
 

See additional SLC5A Antibodies including SLC5A, SLC5A8, Slc5a11 and SLC5A12.

Ordering InformationGene Info
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
SLC5A12 Antibody (S-17) sc-162221 200 µg/ml $279
SLC5A12 (S-17) P sc-162221 P
(peptide)
 100 µg/0.5 ml $61
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human SLC5A12 159963 11p14.2 NM_178498 Q1EHB4
 n/a
Mouse Slc5a12 241612 2 E3 NM_001003915 Q49B93
 N/A
 

SLC5A12 (solute carrier family 5 (sodium/glucose cotransporter), member 12), also known as SMCT2, is a 618 amino acid multi-pass membrane protein that belongs to the sodium:solute symporter (SSF) family. Considered an electroneutral and low-affinity sodium (Na+)-dependent sodium-coupled solute transporter, SLC5A12 mediates the transport of a variety of monocarboxylates, including short-chain fatty acids, lactate, nicotinate and pyruvate. SLC5A12 is thought to participate in the initial step of reabsorption of monocarboxylates from the lumen of the proximal tubule of kidney and small intestine. It is also suggested that SLC5A12 plays a role in the transport of monocarboxylates in retina and is strongly inhibited by ibuprofen, fenoprofen and ketoprofen. SLC5A12 exists as two alternatively spliced isoforms and is encoded by a gene located on human chromosome 11p14.2.