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LAX1 Antibody (N-16): sc-161788

 |  Datasheet

(Based on data analysis)
  • LAX1 Antibody (N-16) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an N-terminal extracellular domain of LAX1 of mouse origin
  • recommended for detection of LAX1 of mouse and rat origin by WB, IF and ELISA
  • blocking peptide, sc-161788 P
 

See additional LAX Antibodies including LAX and LAX1.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
LAX1 Antibody (N-16) sc-161788 200 µg/ml $279
LAX1 (N-16) sc-161788 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
LAX1 siRNA (m) sc-146658 10 µM $258
LAX1 (m)-PR sc-146658-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
LAX1 shRNA Plasmid (m) sc-146658-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
LAX1 shRNA (m) Lentiviral Particles sc-146658-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Mouse Lax1 240754 1 E4 Q8BHB3
 N/A
 

LAX1 (lymphocyte transmembrane adaptor 1), also known as LAX, linker for activation of X cells or membrane-associated adapter protein LAX, is a 398 amino acid single-pass type III membrane protein that negatively regulates lymphocyte signaling. LAX1 is expressed in lymphoid tissues including thymus, spleen and peripheral blood leukocytes, along with several B-cell, T-cell, natural killer and monocyte cell lines. When stimulated by B or T cells, LAX1 becomes dramatically upregulated and also interacts with GRB2, Gads and PI 3-kinase p85 upon phosphorylation. LAX1 exists as two alternatively spliced isoforms that are encoded by a gene located on human chromosome 1. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.