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ARHGAP10 Antibody (D-16): sc-160139

 |  Datasheet

(Based on data analysis)
  • ARHGAP10 Antibody (D-16) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of ARHGAP10 of human origin
  • recommended for detection of ARHGAP10 of mouse, rat and human origin by WB, IF and ELISA; non cross-reactive with other ARHGAP family members; also reactive with additional species, including equine, canine, bovine and avian
  • blocking peptide, sc-160139 P
 

See additional ARHGAP Antibodies including ARHGAP, ARHGAP1, ARHGAP11B, ARHGAP23, ARHGAP25, ARHGAP4, ARHGAP6, ARHGAP8, ARHGAP9, ARHGAP10, ARHGAP11A, ARHGAP12, ARHGAP17, ARHGAP18, ARHGAP19, ARHGAP20, ARHGAP21, ARHGAP22, ARHGAP24, ARHGAP27, ARHGAP28, ARHGAP29, ARHGAP30, ARHGAP36, ARHGAP39 and ARHGAP42.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
ARHGAP10 Antibody (D-16) sc-160139 200 µg/ml $279
ARHGAP10 (D-16) P sc-160139 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ARHGAP10 siRNA (h) sc-89197 10 µM $258
ARHGAP10 siRNA (m) sc-141200 10 µM $258
ARHGAP10 (h)-PR sc-89197-PR 10 µM, 20 µl $23
ARHGAP10 (m)-PR sc-141200-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ARHGAP10 shRNA Plasmid (h) sc-89197-SH 20 µg $520
ARHGAP10 shRNA Plasmid (m) sc-141200-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
ARHGAP10 shRNA (h) Lentiviral Particles sc-89197-V 200 µl $625
ARHGAP10 shRNA (m) Lentiviral Particles sc-141200-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ARHGAP10 79658 4q31.23 A1A4S6
 609746
Mouse Arhgap10 78514 8 C1 Q6Y5D8
 N/A
 

GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in down regulation of their active form. ARHGAP10 (Rho GTPase activating protein 10), also known as GRAF2, PSGAP or PS-GAP, is a 786 amino acid cytoplasmic and cytoskeletal Rho-GTPase activating protein that is expressed at high levels in heart and skeletal muscle. ARHGAP10 regulates caspase-activated ©PAK by inhibiting the protein kinase activity and localization of ©PAK from the nucleus to the perinuclear region. The GAP domain of ARHGAP10 associates with RhoA and Cdc42. ARHGAP10 converts these small GTPases to an inactive GDP-bound state. ARHGAP10 is essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases.