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17β-HSD11 Antibody (S-15): sc-160113

 |  Datasheet

(Based on data analysis)
  • 17β-HSD11 Antibody (S-15) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of 17β-HSD11 of human origin
  • recommended for detection of 17β-HSD11 of mouse, rat and human origin by WB, IF and ELISA; non cross-reactive with other 17β-HSD family members ; also reactive with additional species, including equine and bovine
  • blocking peptide, sc-160113 P
 

See additional 17 beta-HSD Antibodies including 17 beta-HSD, 17beta-HSD2, 17beta-HSD3, 17beta-HSD4, 17beta-HSD6, 17beta-HSD7, 17beta-HSD8, 17beta-HSD11, 17beta-HSD12, 17beta-HSD13 and 17beta-HSD14.

Ordering InformationGene Info
Recommended Support Products:
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WB   IF   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
17β-HSD11 Antibody (S-15) sc-160113 200 µg/ml $279
17β-HSD11 (S-15) P sc-160113 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
17β-HSD11 siRNA (h) sc-89007 10 µM $258
17β-HSD11 siRNA (m) sc-108261 10 µM $258
17β-HSD11 (h)-PR sc-89007-PR 10 µM, 20 µl $23
17β-HSD11 (m)-PR sc-108261-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
17β-HSD11 shRNA Plasmid (h) sc-89007-SH 20 µg $520
17β-HSD11 shRNA Plasmid (m) sc-108261-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
17β-HSD11 shRNA (h) Lentiviral Particles sc-89007-V 200 µl $625
17β-HSD11 shRNA (m) Lentiviral Particles sc-108261-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human HSD17B11 51170 4q22.1 Q8NBQ5
 n/a
Mouse Hsd17b11 114664 5 E5 Q9EQ06
 N/A
 

17∫-HSD11 (17∫ hydroxysteroid dehydrogenase type 11), also designated dehydrogenase/reductase SDR family member 8 (DHRS8) or retinal short-chain dehydrogenase/reductase 2 (retSDR2), belongs to the 17∫-HSD family of proteins, which regulate the availability of steroids within various tissues throughout the body. 17∫-HSD11 is a 300 amino acid protein that converts androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone, suggesting it may participate in androgen metabolism during steroidogenesis. 17∫-HSD11 is widely expressed with highest levels found in retina, pancreas, kidney, liver, lung, adrenal, small intestine, ovary and heart as well as in steroidogenic cells such as syncytiotrophoblasts, sebaceous gland, Leydig cells and granulosa cells of the dominant follicle and corpus luteum. 17-HSD11 localizes on the endoplasmic reticulum (ER) membrane under normal conditions and redistributes to lipid droplets (LDs) upon the induction of LD formation.