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home » Membrane Receptors » Coxsackie and Adenovirus Receptor Antibody / Coxsackie and Adenovirus Receptor Antibodies » CAR (H-300): sc-15405

CAR (H-300) Antibody: sc-15405

  |  Datasheet
  • rabbit polyclonal IgG, 200 µg/ml
  • epitope corresponding to amino acids 1-300 mapping at the N-terminus of CAR of human origin
  • recommended for detection of CAR of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine and porcine
 
Additional Coxsackie and Adenovirus Receptor Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
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WB   IP   IF   IHC(P)   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CXADR 1525 21q21.1 NM_001338 P78310
 602621
Mouse Cxadr 13052 16 C3.1 P97792
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
CAR (H-300) sc-15405 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CAR siRNA (h) sc-29906 10 µM $258
CAR siRNA (m) sc-39919 10 µM $258
CAR (h)-PR sc-29906-PR 10 µM $23
CAR (m)-PR sc-39919-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CAR shRNA Plasmid (h) sc-29906-SH 20 µg $520
CAR shRNA Plasmid (m) sc-39919-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CAR shRNA (h) Lentiviral Particles sc-29906-V 200 µl $625
CAR shRNA (m) Lentiviral Particles sc-39919-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
Hep G2 Cell Lysate sc-2227 500 µg/200 µl $104
mouse brain extract sc-2253 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
A549 Cell Lysate sc-2413 500 µg/200 µl $104
mouse liver extract sc-2256 500 µg/200 µl $104

CAR Background Information
The coxsackie and adenovirus receptor (CAR) mediates viral infection by the binding of various adenoviruses through specific protein interactions. There is a high affinity between the viral knob domain and the extracellular amino- terminal domain (designated D1) of CAR. The D1 domain alone is sufficient for knob binding in transfected cells. Determining the specific interactions between CAR and adenoviruses is imperative in order to further develop gene therapy using viral hosts. CAR is expressed in many human and murine cell types. However, cells that express CAR at low levels are not efficiently infected by adenoviruses. Possible methods of avoiding this problem in certain cell types are by either supplementing CAR or modifying the Ad knob to bind to other receptors.

CAR (H-300) Product Citations
See how others have used CAR (H-300): sc-15405 antibody and or CAR (H-300) antibody conjugates.


17 total citations
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CAR (H-300)
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sc-15405
CAR (H-300): sc-15405. Immunoperoxidase staining of formalin fixed, paraffin-embedded mouse liver showing membrane localization.
sc-15405
CAR (H-300): sc-15405. Immunoperoxidase staining of formalin fixed, paraffin-embedded human prostate cancer showing membrane and cytoplasmic staining of tumor cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
sc-15405
CAR (H-300): sc-15405. Western blot analysis of CAR expression in non-transfected 293T: sc-117752 (A), mouse CAR transfected 293T: sc-118995 (B) and HeLa (C) whole cell lysates.
sc-15405
CAR (H-300): sc-15405. Western blot analysis of CAR expression in mouse liver tissue extract.
sc-15405
CAR (H-300): sc-15405. Immunoperoxidase staining of formalin fixed, paraffin-embedded human urinary bladder tissue showing membrane and cytoplasmic staining of urothelial cells.
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