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Pontin 52 (N-15) Antibody: sc-15259 |
| Datasheet |
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- goat polyclonal IgG, 200 µg/ml
- epitope mapping near the N-terminus of Pontin 52 of human origin
- recommended for detection of Pontin 52 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
- blocking peptide, sc-15259 P
- TransCruz reagent for Gel Supershift and ChIP applications, sc-15259 X, 200 µg/0.1 ml
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Ordering InformationProduct Citations
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| Species |
Gene Name |
Gene ID |
Chromosome Location |
Isoform (mRNA) Accession # |
Protein Accession # |
OMIM™ Number |
| Human |
RUVBL1 |
8607 |
3q21.3 |
NM_003707 |
Q9Y265
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603449 |
| Mouse |
Ruvbl1 |
56505 |
6 D1 |
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P60122
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N/A |
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Pontin 52 Background Information
Pontin 52 is a nuclear matrix protein that is primarily expressed in the nucleus and is also present in the cytoplasm. Pontin 52 is expressed in the nucleoplasm of whole cells, but is not present in the nucleoli. Pontin 52 is also designated RUVBL1, for E. coli RuvB-like 1 protein, or NMP 238, and is the human homolog of rat TIP49. Pontin 52 contains an ATPase/helicase motif and may represent a class of cofactors recruited by transcriptional activation domains that function in diverse pathways. For instance, in vivo, Pontin 52 is complexed with Myc and Reptin 52, which is a Pontin 52 related protein also designated RUVBL2. The interaction of Pontin 52 with Myc is dependent upon a Myc domain essential for oncogenic activity, suggesting that functional Pontin 52 is an essential mediator of Myc oncogenic transformation. The gene encoding human Pontin 52 maps to chromosome 3q21.
| Pontin 52 (N-15) Product Citations |
See how others have used Pontin 52 (N-15): sc-15259 antibody and or Pontin 52 (N-15) antibody conjugates.
3 total citations Loading citations.
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Pontin 52 (N-15)
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Pontin 52 (N-15): sc-15259. Western blot analysis of Pontin 52 expression in SK-BR-3 (A), K-562 (B), KNRK (C) and NIH/3T3 (D) nuclear extracts.
Pontin 52 (N-15): sc-15259. Western blot analysis of Pontin 52 expression in non-transfected: sc-117752 (A) and human Pontin 52 transfected: sc-113069 (B) 293T whole cell lysates. Pontin 52 (N-15): sc-15259. Western blot analysis of Pontin 52 expression in SK-BR-3 whole cell lysate.
Pontin 52 (N-15): sc-15259. Western blot analysis of Pontin 52 expression in non-transfected 293T: sc-117752 (A), human Pontin 52 transfected 293T: sc-175102 (B) and SKBR-3 (C) whole cell lysates. |
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