epitope mapping at the C-terminus of α2B-AR of human origin
recommended for detection of α2B adrenergic receptor of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and porcine
α2B-AR Background Information å2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include three highly homologous subtypes: å2A, å2B, and å2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. åB-adrenergic receptors (a2B-AR) couple to Gi-protein and induce salt-dependent hypertension in response to catecho-lamines. The carboxy-terminal cytoplasmic domain of a2B-AR can associate with proteins, including the guanine nucleotide exchange factor eIF-2B. å2B-AR transcripts are abundant in rat liver and kidney.
α2B-AR (C-19) Product Citations
See how others have used α2B-AR (C-19): sc-1479 antibody and or α2B-AR (C-19) antibody conjugates.