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MCH-1R Antibody (N-15): sc-14510

 |  Datasheet

(Based on data analysis)

  • MCH-1R Antibody (N-15) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of MCH-1R of human origin
  • recommended for detection of MCH-1R of human origin by WB, IF and ELISA
  • blocking peptide, sc-14510 P

See additional MCH Antibodies including MCH-2R, MCH-1R, MCH and pro-MCH.

Also see MCH-1R Inhibitors for functional analysis of cellular responses to MCH-1R.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
MCH-1R Antibody (N-15) sc-14510 200 µg/ml $279
MCH-1R (N-15) P sc-14510 P
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MCH-1R siRNA (h) sc-42017 10 µM $258
MCH-1R (h)-PR sc-42017-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MCH-1R shRNA Plasmid (h) sc-42017-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MCH-1R shRNA (h) Lentiviral Particles sc-42017-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HL-60 Whole Cell Lysate sc-2209 500 µg/200 µl $104
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MCHR1 2847 22q13.2 NM_005297 Q99705

Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic neuropeptide, which is mainly expressed in the hypothalamus (1-2). MCH modulates feeding behavior, aggression, anxiety, arousal and reproductive function in mammals by controlling the release of luteinizing hormone (LH) (1-4). The melanin-concentrating hormone receptor (MCHR, also designated SLC-1) is a glycosylated G-protein coupled receptor (5). MCHR mediates the effects of MCH through Gai and/or Gaq signaling and is expressed in several regions of the brain, including the cerebral cortex, amygdala, thalamus and hypothalamus (1,2,6). MCH and MCHR have also been implicated in stimulating leptin expression and secretion in adipocytes, which suggests that the melanin-concentrating hormone and its receptor may be potential targets for modulating obesity (7).