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pro-MCH Antibody (E-16): sc-14507

 |  Datasheet

(Based on data analysis)

  • pro-MCH Antibody (E-16) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of pro-MCH of human origin
  • recommended for detection of melanin-concentrating hormone of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA
  • blocking peptide, sc-14507 P
  • See 1 citations for pro-MCH Antibody (E-16)
 

See additional MCH Antibodies including MCH-2R, MCH-1R, MCH and pro-MCH.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
pro-MCH Antibody (E-16) sc-14507 200 µg/ml $279
pro-MCH (E-16) P sc-14507 P
(peptide)
100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
pro-MCH siRNA (h) sc-42015 10 µM $258
pro-MCH siRNA (m) sc-42016 10 µM $258
pro-MCH (h)-PR sc-42015-PR 10 µM, 20 µl $23
pro-MCH (m)-PR sc-42016-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
pro-MCH shRNA Plasmid (h) sc-42015-SH 20 µg $520
pro-MCH shRNA Plasmid (m) sc-42016-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
pro-MCH shRNA (h) Lentiviral Particles sc-42015-V 200 µl $625
pro-MCH shRNA (m) Lentiviral Particles sc-42016-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PMCH 5367 12q23.2 NM_002674 P20382
176795
Mouse Pmch 110312 10 C1 P56942
N/A
 


Melanin-concentrating hormone (MCH) is a 19 amino acid cyclic neuropeptide derived from a 165 amino acid pro-MCH precursor. In addition to the hormone, the pro-MCH precursor contains a 144 amino acid mature MCH as well as a 12 amino acid neuropeptide glycine-glutamic acid (NGE) and a 19 amino acid neuropeptide glutamic acid-isoleucine (NEI). Mainly expressed in the hypothalamus, the melanin-concentrating hormone modulates feeding behavior, aggression, anxiety, arousal and reproductive function in mammals by controlling the release of luteinizing hormone (LH). The melanin-concentrating hormone receptor (MCHR, also designated SLC-1) is a glycosylated G protein-coupled receptor. MCHR mediates the effects of MCH through Gåi and/or Gåq signaling and is expressed in several regions of the brain, including the cerebral cortex, amygdala, thalamus and hypothalamus. MCH and MCHR have also been implicated in stimulating leptin expression and secretion in adipocytes, suggesting that the melanin-concentrating hormone and its receptor may be potential targets for modulating obesity.

pro-MCH Antibody (E-16) Product Citations
See how others have used pro-MCH Antibody (E-16) and or pro-MCH Antibody (E-16) conjugates.


1 total citations
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pro-MCH Antibody (E-16) Data
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pro-MCH (E-16): sc-14507. Western blot analysis of human recombinant pro-MCH fusion protein.
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