MAGE-B1 Background Information The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens and are expressed in tumors of different histologic types, but not in normal tissues, with the exception of testis and placenta. Although a large number of MAGE genes have now been identified and extensively studied in tumors of various origin, their function in normal cells remains unknown.
MAGE-B1 (E-19)
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MAGE-B1 (E-19): sc-14294. Western blot analysis of MAGE-B1 expression in non-transfected: sc-117752 (A) and human MAGE-B1 transfected: sc-113270 (B) 293T whole cell lysates.
MAGE-B1 (E-19): sc-14294. Western blot analysis of MAGE-B1 expression in non-transfected: sc-117752 (A) and human MAGE-B1 transfected: sc-176733 (B) 293T whole cell lysates.
