epitope corresponding to amino acids 331-412 mapping at the C-terminus of Adenosine A2A receptor of human origin
recommended for detection of Adenosine A2A-R of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine
Adenosine A2A-R Background Information Adenosine is involved in a variety of processes, including the synthesis of urea, the anti-inflammatory response, and the inhibition of protein synthesis. The Adenosine receptors, including Adenosine A1-R, Adenosine A2A-R, Adenosine A2B-R and Adenosine A3-R, are integral membrane proteins that are members of the G protein-coupled receptor family. Adenosine A1-R mediates ureagenesis in a partially calcium-dependent manner. Adenosine is known to mediate coronary vasodilation via Adenosine A2A-R. Collagen synthesis and total protein synthesis are inhibited in certain cells by Adenosine, acting via the A2B receptors. Activation of Adenosine A3-R inhibits the induction of TNFå and blocks the endotoxin CD14 receptor signal transduction pathway.
Adenosine A2A-R (H-82) Product Citations
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Adenosine A2A-R (H-82)
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Adenosine A2A-R (H-82): sc-13937. Western blot analysis of Adenosine A2A-R expression in SH-SY5Y whole cell lysate.
Adenosine A2A-R (H-82): sc-13937. Immunofluorescence staining of normal mouse intestine frozen section showing membrane staining.
Adenosine A2A-R (H-82): sc-13937. Western blot analysis of Adenosine A2A-R expression in non-transfected: sc-117752 (A) and human Adenosine A2A-R transfected: sc-113350 (B) 293T whole cell lysate.
Adenosine A2A-R (H-82): sc-13937. Western blot analysis of Adenosine A2A-R expression in non-transfected: sc-117752 (A) and human Adenosine A2A-R transfected: sc-127942 (B) 293T whole cell lysates.
