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MIP-1α Antibody (C-16): sc-1381

 |  Datasheet

(Based on data analysis)

  • MIP-1α Antibody (C-16) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the C-terminus of MIP-1α of human origin
  • recommended for detection of MIP-1α of human origin by WB, IP, IF, IHC(P) and ELISA
  • blocking peptide, sc-1381 P
  • See 5 citations for MIP-1α Antibody (C-16)
 

See additional MIP Antibodies including MIP, MIP-1 alpha, MIP-1 beta, MIP-1 gamma, MIP-2, MIP-3 alpha, MIP-3 beta, MIP-4 and MIP-5.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
MIP-1α Antibody (C-16) sc-1381 200 µg/ml $279
MIP-1α (C-16) P sc-1381 P
(peptide)
100 µg/0.5 ml $61
 CRISPR/Cas9 KO and HDR Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MIP-1α CRISPR/Cas9 KO Plasmid (m) sc-422843 20 µg $345
MIP-1α HDR Plasmid (m) sc-422843-HDR 20 µg $385
MIP-1α CRISPR/Cas9 KO Plasmid (h) sc-417845 20 µg $345
MIP-1α HDR Plasmid (h) sc-417845-HDR 20 µg $385
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MIP-1α siRNA (h) sc-43933 10 µM $258
MIP-1α (h)-PR sc-43933-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MIP-1α shRNA Plasmid (h) sc-43933-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MIP-1α shRNA (h) Lentiviral Particles sc-43933-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MIP-1α (h): 293T Lysate sc-114143 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CCL3 6348 17q12 NM_002983 P10147
609423
 


Chemokines are members of a superfamily of small inducible, secreted, pro-inflammatory cytokines. Members of the chemokine family exhibit 20 to 50% homology in their predicted amino acid sequences and are divided into four subfamilies. In C-C (or b) subfamily, the first two cysteines are adjacent. C-C chemokines are chemoattractants and activators for monocytes and T cells. C-C subfamily members include macrophage inflammatory protein (MIP)-1å, MIP-1∫, MIP-2, MIP-3å, MIP-3∫, MIP-4, HCC-1, MIP-5 (or HCC-2), RANTES, MCP-1/2/3 (and the murine homologs JE and MARC), I-309, murine C10 and TCA3. Research has shown that MIP-1∫ is more selective than MIP-1å, primarily attracting CD4+ T lymphocytes, with a preference for T cells of the naive phenotype. MIP-1å is a more potent lymphocyte chemoattractant than MIP-1∫ and exhibits a broader range of chemoattractant specificities. It has been suggested that CD8+ T lymphocytes are involved in the control of HIV infection in vivo by the release of HIV-suppressive factors (HIV-SF). MIP-1å has been identified as one of the major HIV-SFs produced by CD8+ T cells, along with MIP-1∫ and RANTES. Recombinant human MIP-1å acts as an inhibitor of different strains of HIV-1, HIV-2 and SIV infection in a dose-dependent manner.

MIP-1α Antibody (C-16) Product Citations
See how others have used MIP-1α Antibody (C-16) and or MIP-1α Antibody (C-16) conjugates.


5 total citations
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MIP-1α Antibody (C-16) Data
Click on image to enlarge
MIP-1α (C-16): sc-1381. Western blot analysis of human recombinant MIP-1α (A,B).
MIP-1α (C-16): sc-1381. Immunoperoxidase staining of formalin fixed human leukocytes showing cell surface localization.
MIP-1α (C-16): sc-1381. Western blot analysis of human recombinant MIP-1α.
MIP-1α (C-16): sc-1381. Western blot analysis of MIP-1α expression in non-transfected: sc-117752 (A) and human MIP-1α transfected: sc-114143 (B) 293T whole cell lysates.
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