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RNGTT Antibody (N-13): sc-138054

 |  Datasheet

(Based on data analysis)
  • RNGTT Antibody (N-13) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping near the N-terminus of RNGTT of human origin
  • recommended for detection of RNGTT of mouse, rat and human origin by WB, IF and ELISA; also reactive with additional species, including equine, canine, bovine and avian
  • blocking peptide, sc-138054 P
 

See additional RNGTT Antibodies.

Ordering InformationGene Info
Recommended Support Products:
(click button of application of choice)
WB   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
RNGTT Antibody (N-13) sc-138054 200 µg/ml $279
RNGTT (N-13) P sc-138054 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
RNGTT siRNA (h) sc-95119 10 µM $258
RNGTT siRNA (m) sc-153055 10 µM $258
RNGTT (h)-PR sc-95119-PR 10 µM, 20 µl $23
RNGTT (m)-PR sc-153055-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
RNGTT shRNA Plasmid (h) sc-95119-SH 20 µg $520
RNGTT shRNA Plasmid (m) sc-153055-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
RNGTT shRNA (h) Lentiviral Particles sc-95119-V 200 µl $625
RNGTT shRNA (m) Lentiviral Particles sc-153055-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human RNGTT 8732 6q15 O60942
 603512
Mouse Rngtt 24018 4 A5 O55236
 N/A
 

RNGTT (RNA guanylyltransferase and 5'-phosphatase), also known as HCE, HCE1, hCAP or CAP1A, is a 597 amino acid protein that localizes to the nucleus and exists as four alternatively spliced isoforms. Expressed in kidney, lung, heart, brain, liver, testis, skin and muscle, RNGTT acts as a bifunctional mRNA-capping enzyme that exhibits RNA 5'-triphosphatase activity at its N-terminus and mRNA guanylyltransferase activity at its C-terminus. Via its catalytic activity, RNGTT facilitates the first two steps of mRNA cap formation, naming the removal of a gamma-phosphate from the end of nascent mRNA and the subsequent transfer of the phospho residue to the 5’-diphosphate terminus. The gene encoding RNGTT maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome.