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JNK1 Antibody (37): sc-136205

 |  Datasheet

(Based on data analysis)

  • JNK1 Antibody (37) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
  • recommended for detection of JNK1 of mouse, rat and human origin by WB, IP and IF; also reactive with additional species, including canine
 

See additional JNK Antibodies including JNK, JNK1, JNK2 and JNK3.

Also see chemical JNK1 Inhibitors, chemical JNK1 Activators or chemical JNK1 Substrates for functional analysis of cellular responses to JNK1.


Ordering InformationGene Info
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IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
JNK1 Antibody (37) sc-136205 50 µg/0.5 ml $279
 CRISPR/Cas9 KO and HDR Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
JNK1 CRISPR/Cas9 KO Plasmid (m) sc-424053 20 µg $345
JNK1 HDR Plasmid (m) sc-424053-HDR 20 µg $385
JNK1 CRISPR/Cas9 KO Plasmid (h) sc-400048 20 µg $345
JNK1 HDR Plasmid (h) sc-400048-HDR 20 µg $385
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
JNK1 siRNA (h) sc-29380 10 µM $258
JNK1 siRNA (m) sc-29381 10 µM $258
JNK1 siRNA (r) sc-156089 10 µM $258
JNK1 (h)-PR sc-29380-PR 10 µM, 20 µl $23
JNK1 (m)-PR sc-29381-PR 10 µM, 20 µl $23
JNK1 (r)-PR sc-156089-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
JNK1 shRNA Plasmid (h) sc-29380-SH 20 µg $520
JNK1 shRNA Plasmid (m) sc-29381-SH 20 µg $520
JNK1 shRNA Plasmid (r) sc-156089-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
JNK1 shRNA (h) Lentiviral Particles sc-29380-V 200 µl $625
JNK1 shRNA (m) Lentiviral Particles sc-29381-V 200 µl $625
JNK1 shRNA (r) Lentiviral Particles sc-156089-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
A-431 Whole Cell Lysate sc-2201 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
RAW 264.7 Whole Cell Lysate sc-2211 500 µg/200 µl $104
Jurkat Whole Cell Lysate sc-2204 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MAPK8 5599 10q11.22 P45983
601158
Mouse Mapk8 26419 14 B Q91Y86
N/A
 


c-Jun N-terminal kinases (JNKs) phosphorylate and augment transcriptional activity of c-Jun. JNKs originate from three genes that yield 10 isoforms through alternative mRNA splicing, including JNK1a1,JNK1b1, JNK2a1, JNK2b1, and JNK3a1, which represent the p46 isoforms, and JNK1a2, JNK1b2, JNK2a2, JNK2b2, and JNK3b2, which represent the p54 isoforms. JNKs coordinate cell responses to stress and influence regulation of cell growth and transformation. The human JNK1 (PRKM8, SAPK1, MAPK8) gene maps to chromosome 10q11.22 and shares 83% amino acid identity with JNK2. JNK1 is necessary for normal activation and differentiation of CD4 helper T (TH) cells into TH1 and TH2 effector cells. Capsaicin activates JNK1 and p38 in ras-transformed human breast epithelial cells. Nitrogen oxides (NOx) upregulate JNK1 in addition to c-Fos, c-Jun, and other signaling kinases, including MEKK1 and p38.

JNK1 Antibody (37) Data
Click on image to enlarge
JNK1 (37): sc-136205. Western blot analysis of JNK1 expression in PC-12 whole cell lysate.
JNK1 (37): sc-136205. Western blot analysis of human recombinant JNK1/3 fusion protein.
JNK1 (37): sc-136205. Western blot analysis of JNK1 expression in A-431 (A), HeLa (B), RAW 264.7 (C), Jurkat (D) and NIH/3T3 (E) whole cell lysates.
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