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Importin α Antibody (8G5): sc-136204

 |  Datasheet

(Based on data analysis)

  • Importin α Antibody (8G5) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • recommended for detection of Importin α of human origin by WB and ELISA
 

See additional Importin alpha Antibodies.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
Importin α Antibody (8G5) sc-136204 200 µg/ml $279
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human KPNA1 3836 3q21.1 NM_002264 P52294
600686
 


Importin α, also known as karyopherin α, is located primarily at the periphery of the nucleus and is involved in nuclear transport. Importin α acts as a receptor to both monopartite and bipartite nuclear localization signals (NLSs), and when in complex with importin β, targets proteins containing NLSs to the nuclear pore complex (NPC). The importin α-importin β complex binds FXFG nucleoporin repeat regions, and also interacts with Ran-GTP. Binding of Ran-GTP to the importin β subunit leads to the dissociation of the complex. Interaction of importin α with Nup2p facilitates the release of NLSs from importin α.