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karyopherin α2 Antibody (8G5): sc-136204

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  • karyopherin α2 Antibody (8G5) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • recommended for detection of karyopherin α2 of human origin by WB and ELISA
 

See additional karyopherin Antibodies including karyopherin, karyopherin α3, karyopherin α7, karyopherin alpha 1, karyopherin alpha 3, karyopherin beta 1, karyopherin alpha 2, karyopherin beta 2, karyopherin beta 2B, karyopherin beta 3, karyopherin alpha 5 , karyopherin alpha 6 and karyopherin 13.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
karyopherin α2 (8G5) sc-136204 200 µg/ml $279
 CRISPR KO, HDR and Nickase Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
karyopherin β1 CRISPR/Cas9 KO Plasmid (h) sc-401230 20 µg $345
karyopherin β1 HDR Plasmid (h) sc-401230-HDR 20 µg $385
karyopherin β1 Double Nickase Plasmid (h) sc-401230-NIC 20 µg $355
karyopherin β1 Double Nickase Plasmid (h2) sc-401230-NIC-2 20 µg $355
karyopherin α2 CRISPR/Cas9 KO Plasmid (h) sc-401484 20 µg $345
karyopherin α2 HDR Plasmid (h) sc-401484-HDR 20 µg $385
karyopherin α2 Double Nickase Plasmid (h) sc-401484-NIC 20 µg $355
karyopherin α2 Double Nickase Plasmid (h2) sc-401484-NIC-2 20 µg $355
karyopherin β3 CRISPR/Cas9 KO Plasmid (h) sc-402071 20 µg $345
karyopherin β3 HDR Plasmid (h) sc-402071-HDR 20 µg $385
karyopherin β3 Double Nickase Plasmid (h) sc-402071-NIC 20 µg $355
karyopherin β3 Double Nickase Plasmid (h2) sc-402071-NIC-2 20 µg $355
karyopherin α1 CRISPR/Cas9 KO Plasmid (h) sc-402324 20 µg $345
karyopherin α1 HDR Plasmid (h) sc-402324-HDR 20 µg $385
karyopherin α1 Double Nickase Plasmid (h) sc-402324-NIC 20 µg $355
karyopherin α1 Double Nickase Plasmid (h2) sc-402324-NIC-2 20 µg $355
karyopherin β2 CRISPR/Cas9 KO Plasmid (h) sc-403099 20 µg $345
karyopherin β2 HDR Plasmid (h) sc-403099-HDR 20 µg $385
karyopherin β2 Double Nickase Plasmid (h) sc-403099-NIC 20 µg $355
karyopherin β2 Double Nickase Plasmid (h2) sc-403099-NIC-2 20 µg $355
karyopherin α6 CRISPR/Cas9 KO Plasmid (h) sc-403459 20 µg $345
karyopherin α6 HDR Plasmid (h) sc-403459-HDR 20 µg $385
karyopherin α6 Double Nickase Plasmid (h) sc-403459-NIC 20 µg $355
karyopherin α6 Double Nickase Plasmid (h2) sc-403459-NIC-2 20 µg $355
karyopherin 13 CRISPR/Cas9 KO Plasmid (h) sc-404551 20 µg $345
karyopherin 13 HDR Plasmid (h) sc-404551-HDR 20 µg $385
karyopherin 13 Double Nickase Plasmid (h) sc-404551-NIC 20 µg $355
karyopherin 13 Double Nickase Plasmid (h2) sc-404551-NIC-2 20 µg $355
karyopherin α3 CRISPR/Cas9 KO Plasmid (h) sc-410855 20 µg $345
karyopherin α3 HDR Plasmid (h) sc-410855-HDR 20 µg $385
karyopherin α3 Double Nickase Plasmid (h) sc-410855-NIC 20 µg $355
karyopherin α3 Double Nickase Plasmid (h2) sc-410855-NIC-2 20 µg $355
transportin 2 CRISPR/Cas9 KO Plasmid (h) sc-412067 20 µg $345
transportin 2 HDR Plasmid (h) sc-412067-HDR 20 µg $385
transportin 2 Double Nickase Plasmid (h) sc-412067-NIC 20 µg $355
transportin 2 Double Nickase Plasmid (h2) sc-412067-NIC-2 20 µg $355
karyopherin α5 CRISPR/Cas9 KO Plasmid (h) sc-416486 20 µg $345
karyopherin α5 HDR Plasmid (h) sc-416486-HDR 20 µg $385
karyopherin α5 Double Nickase Plasmid (h) sc-416486-NIC 20 µg $355
karyopherin α5 Double Nickase Plasmid (h2) sc-416486-NIC-2 20 µg $355
karyopherin α7 CRISPR/Cas9 KO Plasmid (h) sc-418827 20 µg $345
karyopherin α7 HDR Plasmid (h) sc-418827-HDR 20 µg $385
karyopherin α7 Double Nickase Plasmid (h) sc-418827-NIC 20 µg $355
karyopherin α7 Double Nickase Plasmid (h2) sc-418827-NIC-2 20 µg $355
karyopherin 13 CRISPR/Cas9 KO Plasmid (m) sc-432965 20 µg $345
karyopherin 13 HDR Plasmid (m) sc-432965-HDR 20 µg $385
karyopherin 13 Double Nickase Plasmid (m) sc-432965-NIC 20 µg $355
karyopherin 13 Double Nickase Plasmid (m2) sc-432965-NIC-2 20 µg $355
karyopherin β3 CRISPR/Cas9 KO Plasmid (m) sc-427745 20 µg $345
karyopherin β3 HDR Plasmid (m) sc-427745-HDR 20 µg $385
karyopherin β3 Double Nickase Plasmid (m) sc-427745-NIC 20 µg $355
karyopherin β3 Double Nickase Plasmid (m2) sc-427745-NIC-2 20 µg $355
karyopherin α1 CRISPR/Cas9 KO Plasmid (m) sc-421327 20 µg $345
karyopherin α1 HDR Plasmid (m) sc-421327-HDR 20 µg $385
karyopherin α1 Double Nickase Plasmid (m) sc-421327-NIC 20 µg $355
karyopherin α1 Double Nickase Plasmid (m2) sc-421327-NIC-2 20 µg $355
karyopherin α2 CRISPR/Cas9 KO Plasmid (m) sc-421328 20 µg $345
karyopherin α2 HDR Plasmid (m) sc-421328-HDR 20 µg $385
karyopherin α2 Double Nickase Plasmid (m) sc-421328-NIC 20 µg $355
karyopherin α2 Double Nickase Plasmid (m2) sc-421328-NIC-2 20 µg $355
karyopherin α3 CRISPR/Cas9 KO Plasmid (m) sc-421329 20 µg $345
karyopherin α3 HDR Plasmid (m) sc-421329-HDR 20 µg $385
karyopherin α3 Double Nickase Plasmid (m) sc-421329-NIC 20 µg $355
karyopherin α3 Double Nickase Plasmid (m2) sc-421329-NIC-2 20 µg $355
karyopherin α6 CRISPR/Cas9 KO Plasmid (m) sc-421331 20 µg $345
karyopherin α6 HDR Plasmid (m) sc-421331-HDR 20 µg $385
karyopherin α6 Double Nickase Plasmid (m) sc-421331-NIC 20 µg $355
karyopherin α6 Double Nickase Plasmid (m2) sc-421331-NIC-2 20 µg $355
karyopherin α7 CRISPR/Cas9 KO Plasmid (m) sc-436318 20 µg $345
karyopherin α7 HDR Plasmid (m) sc-436318-HDR 20 µg $385
karyopherin α7 Double Nickase Plasmid (m) sc-436318-NIC 20 µg $355
karyopherin α7 Double Nickase Plasmid (m2) sc-436318-NIC-2 20 µg $355
karyopherin β1 CRISPR/Cas9 KO Plasmid (m) sc-421127 20 µg $345
karyopherin β1 HDR Plasmid (m) sc-421127-HDR 20 µg $385
karyopherin β1 Double Nickase Plasmid (m) sc-421127-NIC 20 µg $355
karyopherin β1 Double Nickase Plasmid (m2) sc-421127-NIC-2 20 µg $355
karyopherin β2 CRISPR/Cas9 KO Plasmid (m) sc-433643 20 µg $345
karyopherin β2 HDR Plasmid (m) sc-433643-HDR 20 µg $385
karyopherin β2 Double Nickase Plasmid (m) sc-433643-NIC 20 µg $355
karyopherin β2 Double Nickase Plasmid (m2) sc-433643-NIC-2 20 µg $355
transportin 2 CRISPR/Cas9 KO Plasmid (m) sc-431835 20 µg $345
transportin 2 HDR Plasmid (m) sc-431835-HDR 20 µg $385
transportin 2 Double Nickase Plasmid (m) sc-431835-NIC 20 µg $355
transportin 2 Double Nickase Plasmid (m2) sc-431835-NIC-2 20 µg $355
 CRISPR Activation Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
karyopherin β1 CRISPR Activation Plasmid (h) sc-401230-ACT 20 µg $345
karyopherin β1 CRISPR Activation Plasmid (h2) sc-401230-ACT-2 20 µg $345
karyopherin β1 Lentiviral Activation Particles (h) sc-401230-LAC 200 µl $395
karyopherin β1 Lentiviral Activation Particles (h2) sc-401230-LAC-2 200 µl $395
karyopherin α2 CRISPR Activation Plasmid (h) sc-401484-ACT 20 µg $345
karyopherin α2 CRISPR Activation Plasmid (h2) sc-401484-ACT-2 20 µg $345
karyopherin α2 Lentiviral Activation Particles (h) sc-401484-LAC 200 µl $395
karyopherin α2 Lentiviral Activation Particles (h2) sc-401484-LAC-2 200 µl $395
karyopherin β3 CRISPR Activation Plasmid (h) sc-402071-ACT 20 µg $345
karyopherin β3 CRISPR Activation Plasmid (h2) sc-402071-ACT-2 20 µg $345
karyopherin β3 Lentiviral Activation Particles (h) sc-402071-LAC 200 µl $395
karyopherin β3 Lentiviral Activation Particles (h2) sc-402071-LAC-2 200 µl $395
karyopherin α1 CRISPR Activation Plasmid (h) sc-402324-ACT 20 µg $345
karyopherin α1 CRISPR Activation Plasmid (h2) sc-402324-ACT-2 20 µg $345
karyopherin α1 Lentiviral Activation Particles (h) sc-402324-LAC 200 µl $395
karyopherin α1 Lentiviral Activation Particles (h2) sc-402324-LAC-2 200 µl $395
karyopherin β2 CRISPR Activation Plasmid (h) sc-403099-ACT 20 µg $345
karyopherin β2 CRISPR Activation Plasmid (h2) sc-403099-ACT-2 20 µg $345
karyopherin β2 Lentiviral Activation Particles (h) sc-403099-LAC 200 µl $395
karyopherin β2 Lentiviral Activation Particles (h2) sc-403099-LAC-2 200 µl $395
karyopherin α6 CRISPR Activation Plasmid (h) sc-403459-ACT 20 µg $345
karyopherin α6 CRISPR Activation Plasmid (h2) sc-403459-ACT-2 20 µg $345
karyopherin α6 Lentiviral Activation Particles (h) sc-403459-LAC 200 µl $395
karyopherin α6 Lentiviral Activation Particles (h2) sc-403459-LAC-2 200 µl $395
karyopherin 13 CRISPR Activation Plasmid (h) sc-404551-ACT 20 µg $345
karyopherin 13 CRISPR Activation Plasmid (h2) sc-404551-ACT-2 20 µg $345
karyopherin 13 Lentiviral Activation Particles (h) sc-404551-LAC 200 µl $395
karyopherin 13 Lentiviral Activation Particles (h2) sc-404551-LAC-2 200 µl $395
karyopherin α3 CRISPR Activation Plasmid (h) sc-410855-ACT 20 µg $345
karyopherin α3 CRISPR Activation Plasmid (h2) sc-410855-ACT-2 20 µg $345
karyopherin α3 Lentiviral Activation Particles (h) sc-410855-LAC 200 µl $395
karyopherin α3 Lentiviral Activation Particles (h2) sc-410855-LAC-2 200 µl $395
transportin 2 CRISPR Activation Plasmid (h) sc-412067-ACT 20 µg $345
transportin 2 CRISPR Activation Plasmid (h2) sc-412067-ACT-2 20 µg $345
transportin 2 Lentiviral Activation Particles (h) sc-412067-LAC 200 µl $395
transportin 2 Lentiviral Activation Particles (h2) sc-412067-LAC-2 200 µl $395
karyopherin α5 CRISPR Activation Plasmid (h) sc-416486-ACT 20 µg $345
karyopherin α5 CRISPR Activation Plasmid (h2) sc-416486-ACT-2 20 µg $345
karyopherin α5 Lentiviral Activation Particles (h) sc-416486-LAC 200 µl $395
karyopherin α5 Lentiviral Activation Particles (h2) sc-416486-LAC-2 200 µl $395
karyopherin α7 CRISPR Activation Plasmid (h) sc-418827-ACT 20 µg $345
karyopherin α7 CRISPR Activation Plasmid (h2) sc-418827-ACT-2 20 µg $345
karyopherin α7 Lentiviral Activation Particles (h) sc-418827-LAC 200 µl $395
karyopherin α7 Lentiviral Activation Particles (h2) sc-418827-LAC-2 200 µl $395
karyopherin 13 CRISPR Activation Plasmid (m) sc-432965-ACT 20 µg $345
karyopherin 13 CRISPR Activation Plasmid (m2) sc-432965-ACT-2 20 µg $345
karyopherin 13 Lentiviral Activation Particles (m) sc-432965-LAC 200 µl $395
karyopherin 13 Lentiviral Activation Particles (m2) sc-432965-LAC-2 200 µl $395
karyopherin β3 CRISPR Activation Plasmid (m) sc-427745-ACT 20 µg $345
karyopherin β3 CRISPR Activation Plasmid (m2) sc-427745-ACT-2 20 µg $345
karyopherin β3 Lentiviral Activation Particles (m) sc-427745-LAC 200 µl $395
karyopherin β3 Lentiviral Activation Particles (m2) sc-427745-LAC-2 200 µl $395
karyopherin α1 CRISPR Activation Plasmid (m) sc-421327-ACT 20 µg $345
karyopherin α1 CRISPR Activation Plasmid (m2) sc-421327-ACT-2 20 µg $345
karyopherin α1 Lentiviral Activation Particles (m) sc-421327-LAC 200 µl $395
karyopherin α1 Lentiviral Activation Particles (m2) sc-421327-LAC-2 200 µl $395
karyopherin α2 CRISPR Activation Plasmid (m) sc-421328-ACT 20 µg $345
karyopherin α2 CRISPR Activation Plasmid (m2) sc-421328-ACT-2 20 µg $345
karyopherin α2 Lentiviral Activation Particles (m) sc-421328-LAC 200 µl $395
karyopherin α2 Lentiviral Activation Particles (m2) sc-421328-LAC-2 200 µl $395
karyopherin α3 CRISPR Activation Plasmid (m) sc-421329-ACT 20 µg $345
karyopherin α3 CRISPR Activation Plasmid (m2) sc-421329-ACT-2 20 µg $345
karyopherin α3 Lentiviral Activation Particles (m) sc-421329-LAC 200 µl $395
karyopherin α3 Lentiviral Activation Particles (m2) sc-421329-LAC-2 200 µl $395
karyopherin α6 CRISPR Activation Plasmid (m) sc-421331-ACT 20 µg $345
karyopherin α6 CRISPR Activation Plasmid (m2) sc-421331-ACT-2 20 µg $345
karyopherin α6 Lentiviral Activation Particles (m) sc-421331-LAC 200 µl $395
karyopherin α6 Lentiviral Activation Particles (m2) sc-421331-LAC-2 200 µl $395
karyopherin α7 CRISPR Activation Plasmid (m) sc-436318-ACT 20 µg $345
karyopherin α7 CRISPR Activation Plasmid (m2) sc-436318-ACT-2 20 µg $345
karyopherin α7 Lentiviral Activation Particles (m) sc-436318-LAC 200 µl $395
karyopherin α7 Lentiviral Activation Particles (m2) sc-436318-LAC-2 200 µl $395
karyopherin β1 CRISPR Activation Plasmid (m) sc-421127-ACT 20 µg $345
karyopherin β1 CRISPR Activation Plasmid (m2) sc-421127-ACT-2 20 µg $345
karyopherin β1 Lentiviral Activation Particles (m) sc-421127-LAC 200 µl $395
karyopherin β1 Lentiviral Activation Particles (m2) sc-421127-LAC-2 200 µl $395
karyopherin β2 CRISPR Activation Plasmid (m) sc-433643-ACT 20 µg $345
karyopherin β2 CRISPR Activation Plasmid (m2) sc-433643-ACT-2 20 µg $345
karyopherin β2 Lentiviral Activation Particles (m) sc-433643-LAC 200 µl $395
karyopherin β2 Lentiviral Activation Particles (m2) sc-433643-LAC-2 200 µl $395
transportin 2 CRISPR Activation Plasmid (m) sc-431835-ACT 20 µg $345
transportin 2 CRISPR Activation Plasmid (m2) sc-431835-ACT-2 20 µg $345
transportin 2 Lentiviral Activation Particles (m) sc-431835-LAC 200 µl $395
transportin 2 Lentiviral Activation Particles (m2) sc-431835-LAC-2 200 µl $395
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human KPNA1 3836 3q21.1 NM_002264 P52294
600686
 


Protein transport across the nucleus is a selective, multi-step process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Two cytosolic factors centrally involved in the recognition and docking process are the karyopherin a1 and karyopherin ∫1 subunits. Karyopherin a1 functions in the recognition and targeting of substrates destined for nuclear import, while karyopherin ∫1 serves as an adapter, tethering the karyopherin å1/substrate complex to docking proteins on the nuclear envelope termed nucleoporins. Karyopherin a2 has been shown to complex with Epstein-Barr virus nuclear antigen 1 (EBNA1). Certain RNA-binding proteins are imported to the nucleus by karyopherin ∫2, and karyopherin ∫3 appears to be involved in the import of some ribosomal proteins.

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karyopherin α2 Antibody (8G5) Data
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karyopherin α2 (8G5): sc-136204. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing nuclear and cytoplasmic staining of cells in seminiferous ducts and Leydig cells.
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