Welcome to Santa Cruz Biotechnology!
SCBT Home
Home » Kinases and Phosphatases » PKC Antibodies » p-PKC α Antibody (pT638.35): sc-136018

p-PKC α Antibody (pT638.35): sc-136018

 |  Datasheet

(Based on data analysis)

  • p-PKC α Antibody (pT638.35) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
  • recommended for detection of Thr 638 phosphorylated PKC α of human origin by WB and IP
  • See 2 citations for p-PKC α Antibody (pT638.35)
 

See additional PKC Antibodies including PKC, PKC alpha, PKC beta, PKC delta, PKC epsilon, PKC eta, PKC gamma, PKC iota, PKC lambda, PKC mu, PKC nu, PKC theta, PKC zeta and Pkc1.

Also see PKC alpha Inhibitors, PKC alpha Activators, PKC alpha Substrates or PKC alpha Substrates for functional analysis of cellular responses to PKC alpha and PKC alpha.


Ordering InformationProduct CitationsGene Info
Recommended Support Products:
(click button of application of choice)
WB   IP   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-PKC α Antibody (pT638.35) sc-136018 50 µg/0.5 ml $279
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKC α siRNA (h) sc-36243 10 µM $258
PKC α siRNA (h2) sc-44227 10 µM $258
PKC α (h)-PR sc-36243-PR 10 µM, 20 µl $23
PKC α (h2)-PR sc-44227-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKC α shRNA Plasmid (h) sc-36243-SH 20 µg $520
PKC α shRNA Plasmid (h2) sc-44227-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
PKC α shRNA (h) Lentiviral Particles sc-36243-V 200 µl $625
PKC α shRNA (h2) Lentiviral Particles sc-44227-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HeLa + PMA nuclear extract sc-2121 250 µg/0.05 ml $143
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human PRKCA 5578 17q24.2 P17252
 176960
 

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function (1,2). PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids (3). Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC (4,5). PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (å, ∫I, ∫II and ©) and novel (n) PKC isoforms (∂, é , Ω, h and †) (6). PKC isoforms can be activated through tyrosine phosphorylation and catalytically activated upon treatment with H2O2 (7,8). The Tyr 155, 525, 523 and 565 residues in the catalytic domain are crucial for activation of these enzymes (7,8). The residue Ser 643 appears to be an autophosphorylation site (9).

p-PKC α Antibody (pT638.35) Product Citations
See how others have used p-PKC α Antibody (pT638.35) and or p-PKC α Antibody (pT638.35) conjugates.


2 total citations
Loading citations.
 
p-PKC α Antibody (pT638.35) Data
Click on image to enlarge
sc-136018
p-PKC α (pT638.35): sc-136018. Western blot analysis of PKC α phosphorylation in Calyculin A and Okadaic Acid-treated Jurkat whole cell lysates either untreated (A) or treated (B) with lambda phosphatase.
Download
Datasheets
Get Adobe Acrobat Reader