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p-Cbl Antibody (pY700.47): sc-136013

 |  Datasheet

(Based on data analysis)

  • p-Cbl Antibody (pY700.47) is a mouse monoclonal IgG1 provided at 50 µg/0.5 ml
  • recommended for detection of Tyr 700 phosphorylated Cbl of human origin by WB, IP and IF
 

See additional Cbl Antibodies including Cbl, Cbl-b and Cbl-3.

Ordering InformationGene Info
Recommended Support Products:
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WB   IP   IF   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-Cbl Antibody (pY700.47) sc-136013 50 µg/0.5 ml $279
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Cbl siRNA (h) sc-29242 10 µM $258
Cbl (h)-PR sc-29242-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Cbl shRNA Plasmid (h) sc-29242-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Cbl shRNA (h) Lentiviral Particles sc-29242-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Jurkat + pervanadate Cell Lysate sc-24716 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CBL 867 11q23.3 P22681
165360
 


The c-Cbl proto-oncogene has been identified as the cellular homolog of the v-Cbl oncogene isolated from an NFS/N mouse that developed a pre-B cell lymphoma following infection with the replication-competent Cas-Br-M murine leukemic virus. c-Cbl is expressed at relatively high levels in a wide range of hematopoietic tumor cell lines as well as in normal tissues such as thymus and testis. The c-Cbl gene product has been identified as a cytoplasmic protein with apparent DNA binding and dimerization domains characteristic of transcription factors. A single c-Cbl locus termed CBL2 has been mapped to human chromosome 11q23. This region of chromosome 11 is involved in translocations and deletions in a broad range of leukemias; c-Cbl has been found to be translocated from chromosome 11 in leukemias with either t(4;11) or t(11;14) abnormalities.

p-Cbl Antibody (pY700.47) Data
Click on image to enlarge
p-Cbl (pY700.47): sc-136013. Western blot analysis of Cbl phosphorylation in untreated (A) and pervanadate-treated (B) Jurkat whole cell lysates.
p-Cbl (pY700.47): sc-136013. Immunofluorescence staining of paraformaldehyde-fixed untreated (A) and pervanadate-treated (B) serum-starved Eahy cells showing cytoplasmic localization.
p-Cbl (pY700.47): sc-136013. Western blot analysis of Cbl phosphorylation in untreated (A), pervanadate treated (B) and pervanadate and lambda protein phosphatase treated (C) Jurkat whole cell lysates.
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