RP105 Background Information RP105 is a mouse B-cell surface molecule that transmits a growth-promoting signal and is implicated in the life/death decision of B cells. RP105 has tandem repeats of a leucine-rich motif in its extracellular domain that are presumed to be involved in protein-protein interactions. The amino acid sequence of human RP105 is highly homologous to that of mouse RP105; human RP105 shares 74% identity with the mouse protein, as well as the leucine-rich motif. Surface expression of RP105 is enhanced in the presence of MD1, although this expression is restricted to CD19-positive B cells. RP105 demonstrates predominant expression on mature B cells in mantle zones; very little expression is observed in germinal centers.
RP105 (RP/14) Product Citations
See how others have used RP105 (RP/14): sc-13592 antibody and or RP105 (RP/14) antibody conjugates.
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RP105 (RP/14)
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RP105 (RP/14) PE: sc-13592 PE. FCM analysis of mouse peripheral blood leukocytes. Quadrant markers were set based on the isotype control, normal rat IgG2a: sc-2872.
RP105 (RP/14) FITC: sc-13592 FITC. FCM analysis of mouse peripheral blood leukocytes. Quadrant markers were set based on the isotype control, normal rat IgG2a: sc-2831.
