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p-NFATc4 Antibody (22.S168/170): sc-135770

 |  Datasheet

(Based on data analysis)
  • p-NFATc4 Antibody (22.S168/170) is a mouse monoclonal IgG1 provided at 200 µg/ml
  • raised against a short amino acid sequence containing dually phosphorylated Ser 168 and Ser 170 of NFATc4 of human origin
  • recommended for detection of Ser 168 and Ser 170 dually phosphorylated NFATc4 of human origin by WB and ELISA
  • TransCruz reagent for Gel Supershift and ChIP applications, sc-135770 X, 200 µg/0.1 ml
 

See additional NFAT Antibodies including NFAT, NFATc1, NFATc2, NFATc3, NFATc4 and NFAT5.

Ordering InformationGene Info
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WB   siRNA  
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-NFATc4 Antibody (22.S168/170) sc-135770 200 µg/ml $279
p-NFATc4 Antibody (22.S168/170) X sc-135770 X 200 µg/0.1 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
NFATc4 siRNA (h) sc-38115 10 µM $258
NFATc4 siRNA (h) sc-38115-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
NFATc4 shRNA Plasmid (h) sc-38115-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
NFATc4 shRNA (h) Lentiviral Particles sc-38115-V 200 µl $625
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human NFATC4 4776 14q12 Q14934
 602699
 

NFATc4 (nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4) is a member of the nuclear factors of activated T cells DNA-binding transcription complex that influences cytokine gene expression, cardiac hypertrophy, and adipocyte differentiation. This complex consists of at least two components: a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Other members of this family participate in the formation of this complex. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues, including Serine-168 and Serine-170, in the NFAT homology domain of NFATc4.