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p-Synapsin Ia/b Antibody (Ser 62/Ser 67): sc-135709

 |  Datasheet

(Based on data analysis)

  • p-Synapsin Ia/b Antibody (Ser 62/Ser 67) is a rabbit polyclonal IgG provided at 100µl
  • recommended for detection of Ser 62 and Ser 67 dually phosphorylated Synapsin Ia/b of mouse and rat origin by WB and IP; also reactive with additional species, including bovine
  • See 2 citations for p-Synapsin Ia/b Antibody (Ser 62/Ser 67)
 

See additional Synapsin Antibodies including Synapsin, Synapsin Ia/b, Synapsin IIa and Synapsin IIIa.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
p-Synapsin Ia/b Antibody (Ser 62/Ser 67) sc-135709 100 µl $279
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
Lambda Phosphatase sc-200312 100000 units in 0.25 ml $462
Lambda Phosphatase sc-200312A 20000 units in 0.05 ml $116
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Synapsin Ia/b siRNA (m) sc-37013 10 µM $258
Synapsin Ia/b (m)-PR sc-37013-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Synapsin Ia/b shRNA Plasmid (m) sc-37013-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Synapsin Ia/b shRNA (m) Lentiviral Particles sc-37013-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
rat cerebellum extract sc-2398 500 µg/200 µl $104
rat brain extract sc-2392 500 µg/200 µl $104
mouse brain extract sc-2253 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Mouse Syn1 20964 X A1.3 O88935
 N/A
 

Synapsin I, which exists as two alternatively spliced isoforms designated Synapsin Ia and Synapsin Ib, has been characterized as one of the major phosphoproteins in nerve terminals and is thought to be involved in the regulation of neurotransmitter release. Synapsin I cross-links synaptic vesicles and the cytoskeleton, and the interactions of synapsins with actin filaments and synaptic vesicles are regulated by phosphorylation by calmodulin-dependent protein kinase II and cAMP-dependent protein kinase. Posttranslational modifications of Synapsin I result in phosphorylation of the protein at different sites and by different kinases. The Ser 553 residue of Synapsin I is phosphorylated in vivo. This phosphorylation site is immediately followed by a proline, suggesting that Synapsin I is an in vivo substrate of the proline-directed protein kinase, Cdk5.

p-Synapsin Ia/b Antibody (Ser 62/Ser 67) Product Citations
See how others have used p-Synapsin Ia/b Antibody (Ser 62/Ser 67) and or p-Synapsin Ia/b Antibody (Ser 62/Ser 67) conjugates.


2 total citations
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p-Synapsin Ia/b Antibody (Ser 62/Ser 67) Data
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sc-135709
p-Synapsin Ia/b (Ser 62/Ser 67): sc-135709. Western blot analysis of Synapsin Ia/b phosphorylation in rat prefrontal cortex tissue extract. Blots were probed with p-Synapsin Ia/b (Ser 62/Ser 67): sc-135709 (A) and p-Synapsin Ia/b (Ser 62/Ser 67): sc-135709 preincubated with its cognate phosphorylated peptide (B).
sc-135709
Western blot analysis of Synapsin Ia/b phosphorylation in untreated (A, C) and lambda protein phosphatase treated (B, D) rat brain tissue extracts. Antibodies tested include p-Synapsin Ia/b (Ser 62/Ser 67): sc-135709 (A, B) and Synapsin Ia/b (H-170): sc-20780 (C, D).
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