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KVβ Antibody (H-300): sc-134864

 |  Datasheet

(Based on data analysis)
  • KVβ Antibody (H-300) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 120-419 mapping at the C-terminus of KVβ.1 of human origin
  • recommended for detection of KVβ.1, KVβ.2, and to a lesser extent, KVβ.3 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
 
Full-length KVβ protein sequence with immunogen highlighted:
MLAARTGAAGSQISEENTKLRRQSGFSVAGKDKSPKKASENAKDSSLSPSGESQLRARQLALLREVEMNWYLKLCDLSSEHTTVCTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS

See additional KV Antibodies including KV, KV beta, KV beta 1, KV beta 2, KV beta 3, KV1.1, KV1.2, KV1.3, KV1.4, KV1.5, KV1.6, KV1.7, KV2.1, KV2.2, KV3.1, KV3.2, KV4.1, KV4.2, KV4.3, KV6.3, KV9.1, KV9.2 and KV9.3.

Also see KV Inhibitors for functional analysis of cellular responses to KV.


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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
KVβ Antibody (H-300) sc-134864 200 µg/ml $279

Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming å subunits (KV), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV∫, also known as KCNAB1 (potassium voltage-gated channel, shaker-related subfamily, beta member 1), is a 419 amino acid accessory K+ channel protein that exists as three alternatively spliced isoforms and regulates the activity of the pore-forming å subunit. It is expressed in brain, with highest levels detected in caudate nucleus, hippocampus and thalamus.