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AHCYL1/2 Antibody (H-160): sc-134650

 |  Datasheet

(Based on data analysis)

  • AHCYL1/2 Antibody (H-160) is a rabbit polyclonal IgG provided at 200 µg/ml
  • epitope corresponding to amino acids 1-160 mapping at the N-terminus of AHCYL1 of human origin
  • recommended for detection of AHCYL1 and AHCYL2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, bovine, porcine and avian
 
Full-length AHCYL1/2 protein sequence with immunogen highlighted:
MSMPDAMPLPGVGEELKQAKEIEDAEKYSFMATVTKAPKKQIQFADDMQEFTKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDDEVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQDMSALISLRKRAQGEKPLAGAKIVGCTHITAQTALIETLCALGAQCRWSACNIYSTQNEVAAALAEAGVAVFAWKGESEDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPNVFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSVTKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGEVGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKLNEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGHSNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLLAEGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRYKQDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLGLNKNGPFKPNYYRY

See additional AHCYL Antibodies including AHCYL, AHCYL1 and AHCYL2.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
AHCYL1/2 Antibody (H-160) sc-134650 200 µg/ml $279

AHCYL1 (S-adenosylhomocysteine hydrolase-like 1), also known as DCAL, IRBIT or PRO0233, and AHCYL2 (S-adenosylhomocysteine hydrolase-like 2) are endoplasmic reticulum (ER) proteins involved in amino acid biosynthesis. Expressed in dentritic blood cells (DCs), AHCYL1 and AHCYL2 function to catalyze the H(2)O-dependent conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine, a reaction that uses NAD as a cofactor. Additionally, AHCYL1 contains a PDZ-binding domain and a PEST region through which it can interact with IP3R-I (inositol 1,4,5-trisphosphate (IP3) receptor-I), a protein involved in various signaling pathways. This interaction lowers the affinity of IP3R-1 for its substrate, IP3, thereby decreasing the rate of IP3-IP3R-I binding.

AHCYL1/2 Antibody (H-160) Data
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sc-134650
AHCYL1/2 (H-160): sc-134650. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.
sc-134650
AHCYL1/2 (H-160): sc-134650. Western blot analysis of AHCYL1/2 expression in HeLa (A) and ME-180 (B) whole cell lysates.
sc-134650
AHCYL1/2 (H-160): sc-134650. Western blot analysis of AHCYL1 expression in non-transfected: sc-117752 (A) and mouse AHCYL1 transfected: sc-118278 (B) 293T whole cell lysates.
sc-134650
AHCYL1/2 (H-160): sc-134650. Western blot analysis of AHCYL1 expression in non-transfected: sc-117752 (A) and human AHCYL1 transfected: sc-127950 (B) 293T whole cell lysates.
sc-134650
AHCYL1/2 (H-160): sc-134650. Western blot analysis of AHCYL1 expression in non-transfected: sc-117752 (A) and human AHCYL1 transfected: sc-158241 (B) 293T whole cell lysates.
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