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home » Signaling Intermediates » TIS11 Antibody / TIS11 Antibodies » TIS11B (A-21): sc-134091

TIS11B (A-21) Antibody: sc-134091

  |  Datasheet
  • rabbit polyclonal IgG, 50 µg/0.5 ml
  • recommended for detection of TIS11B of mouse, rat and human origin by WB, IP and ELISA; also reactive with additional species, including canine
 
Additional TIS11 Antibodies ...
 
Ordering Information
Recommended Support Products:
(click button of application of choice)
WB   IP   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ZFP36L1 677 14q24.1 Q07352
 601064
Mouse Zfp36l1 12192 12 C3 P23950
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
TIS11B (A-21) sc-134091 50 µg/0.5 ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TIS11B siRNA (h) sc-76672 10 µM $258
TIS11B siRNA (m) sc-76673 10 µM $258
TIS11B (h)-PR sc-76672-PR 10 µM $23
TIS11B (m)-PR sc-76673-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TIS11B shRNA Plasmid (h) sc-76672-SH 20 µg $520
TIS11B shRNA Plasmid (m) sc-76673-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
TIS11B shRNA (h) Lentiviral Particles sc-76672-V 200 µl $625
TIS11B shRNA (m) Lentiviral Particles sc-76673-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104

TIS11B Background Information
TIS11B (tetradecanoyl phorbol acetate-inducible-sequence 11b), also known as ZFP36L1, BRF1 (butyrate response factor 1), ERF1 (EGF-response factor 1), cMG1, Berg36 or RNF162B, is a member of the tristetraprolin family. Tristetraprolin (TTP), or TIS11, is a zinc-binding protein encoded by the immediate-early response gene, Zfp-36. TIS11B, a relative of TTP, localizes to the nucleus and may function as a transcription factor involved in regulating the growth factor response. It is an evolutionarily conserved protein containing two C3H1-type zinc fingers and a repeating cys-his motif. TIS11B is an mRNA binding protein and is known to interact with the 3’-untranslated region of VEGF mRNA, thereby decreasing its stability. This suggests that TIS11B is a potential target in antiangiogenic therapy. In addition, TIS11B may also be an important regulator of myogenesis, as its expression is upregulated during murine myoblast differentiation.
TIS11B (A-21)
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sc-134091
TIS11B (A-21): sc-134091. Western blot analysis of TIS11B expression in HeLa whole cell lysate.
sc-134091
TIS11B (A-21): sc-134091. Western blot analysis of TIS11B expression in human placenta tissue extract.
sc-134091
TIS11B (A-21): sc-134091. Western blot analysis of TIS11B expression in JAR (A), Ramos (B), A549 (C) and HT-1080 (D) whole cell lysates.
sc-134091
TIS11B (A-21): sc-134091. Western blot analysis of TIS11B expression in HeLa (A), K-562 (B), THP-1 (C), A549 (D), KNRK (E) and WI 38 (F) nuclear extracts.
sc-134091
TIS11B (A-21): sc-134091. Western blot analysis of TIS11B expression in K-562 (A) and THP-1 (B) nuclear extracts.
sc-134091
TIS11B (A-21): sc-134091. Western blot analysis of TIS11B expression in JAR (A), Ramos (B), A549 (C), MCR7 (D) and SW480 (E) whole cell lysates.
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