TEF-3 Background Information TEF-3, also known as TEAD4 (TEA domain family member 4), RTEF1, EFTR-2, TEFR-1, TCF13L1 or hRTEF-1B, is a 427 amino acid member of the transcriptional enhancer factor (TEF) family of proteins that are characterized by the presence of a TEA DNA-binding domain. Localized to the nucleus and expressed primarily in skeletal muscle, TEF-3 functions as a transcriptional regulator by binding specifically and non-cooperatively to the M-CAT motif found in the promotors of muscle-specific genes, thereby directing their subsequent expression. TEF-3 contains one TEA DNA-binding domain and is expressed as multiple isoforms due to alternative splicing events.
TEF-3 (W-21)
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TEF-3 (W-21): sc-134071. Western blot analysis of human TEF-3 transfected 293T whole cell lysate.
TEF-3 (W-21): sc-134071. Western blot analysis of TEF-3 expression in non-transfected: sc-110760 (A) and human TEF-3 transfected: sc-113218 (B) 293 whole cell lysates and HeLa nuclear extract (C).
