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HBO1 Antibody (N-18): sc-13283

 |  Datasheet

(Based on data analysis)

  • HBO1 Antibody (N-18) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping at the N-terminus of HBO1 of human origin
  • recommended for detection of HBO1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
  • blocking peptide, sc-13283 P
  • See 3 citations for HBO1 Antibody (N-18)
 

See additional HBO1 Antibodies.

Ordering InformationProduct CitationsGene Info
Recommended Support Products:
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WB   IP   IF   IHC(P)   siRNA  
Set Currency

 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
HBO1 Antibody (N-18) sc-13283 200 µg/ml $279
HBO1 (N-18) P sc-13283 P
(peptide)
 100 µg/0.5 ml $61
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HBO1 siRNA (h) sc-35530 10 µM $258
HBO1 siRNA (m) sc-35531 10 µM $258
HBO1 (h)-PR sc-35530-PR 10 µM, 20 µl $23
HBO1 (m)-PR sc-35531-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HBO1 shRNA Plasmid (h) sc-35530-SH 20 µg $520
HBO1 shRNA Plasmid (m) sc-35531-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HBO1 shRNA (h) Lentiviral Particles sc-35530-V 200 µl $625
HBO1 shRNA (m) Lentiviral Particles sc-35531-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104
Caki-1 Cell Lysate sc-2224 500 µg/200 µl $104
SK-BR-3 nuclear extract sc-2134 250 µg/0.05 ml $143
A-673 nuclear extract sc-2128 250 µg/0.05 ml $143
HeLa nuclear extract sc-2120 250 µg/0.05 ml $143
A-431 nuclear extract sc-2122 250 µg/0.05 ml $143
HBO1 (m): 293T Lysate sc-125432 100 µg/200 µl $205
HBO1 (h): 293T Lysate sc-115259 100 µg/200 µl $205
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human MYST2 11143 17q21.33 NM_007067 O95251
 609880
Mouse Myst2 217127 11 D Q5SVQ0
 N/A
 

In the cell, transcription is regulated in part by the histone modification of chromatin. Specifically, histone acetyltransferase proteins and their associated complexes function with co-activators to regulate transcription. One family of histone acetyltransferases is the MYST family of transcriptional silencers, which is linked to ORC (origin recognition complex) function. The ORC is an initiator protein for DNA replication and mediates the acetylation of chromatin to control both DNA replication and gene expression. HBO1 (histone acetyltransferase binding to ORC) is a MYST family protein that interacts with ORC1, the largest subunit of the human ORC complex. HBO1 is a nuclear protein that is highly expressed in human testis. In addition to binding ORC, HBO1 represses AR (androgen receptor)-mediated transcription by binding AR through its N-terminal transcriptional repression domain. HBO1 may play a role in regulating AR-dependent gene transcription in normal and prostate cancer cells.

HBO1 Antibody (N-18) Product Citations
See how others have used HBO1 Antibody (N-18) and or HBO1 Antibody (N-18) conjugates.


3 total citations
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HBO1 Antibody (N-18) Data
Click on image to enlarge
sc-13283
HBO1 (N-18): sc-13283. Western blot analysis of HBO1 expression in HeLa whole cell lysate.
sc-13283
HBO1 (N-18): sc-13283. Western blot analysis of HBO1 expression in non-transfected: sc-117752 (A) and human HBO1 transfected: sc-115259 (B) 293T whole cell lysates.
sc-13283
HBO1 (N-18): sc-13283. Western blot analysis of HBO1 expression in non-transfected: sc-117752 (A) and mouse HBO1 transfected: sc-125432 (B) 293T whole cell lysates.
sc-13283
HBO1 Antibody (N-18): sc-13283. Immunoperoxidase staining of formalin fixed, paraffin-embedded human upper stomach tissue showing nuclear and cytoplasmic staining of glandular cells.
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