epitope mapping near the N-terminus of LAPTM4A of human origin
recommended for detection of LAPTM4A of mouse, rat and human origin by WB, IF and ELISA; non cross-reactive with LAPTM4B; also reactive with additional species, including equine, canine, bovine and porcine
LAPTM4A Background Information Lysosomal-associated transmembrane protein 4A (LAPTM4A), also known as Golgi 4-transmembrane spanning transporter MTP, is a 233 amino acid protein belonging to the LAPTM4/LAPTM5 transporter family. LAPTM4A is subcellularly localized to the intracytoplasmic membrane and has the potential to reside in intracellular membrane-bound compartments. LAPTM4A is thought to function as a transporter of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of intracellular compartments. LAPTM4A is predicted to have four transmembrane domains, with the C-terminal domain being required for retention of the protein within intracellular membranes.
