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home » Neurobiology » CASK Antibody / CASK Antibodies » CASK (C-6): sc-13158

CASK (C-6) Antibody: sc-13158

  |  Datasheet
  • mouse monoclonal IgG2b; 200 µg/ml
  • raised against amino acids 353-459 of CASK of human origin
  • recommended for detection of CASK of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine, canine, bovine, porcine and avian
 
Additional CASK Antibodies ...
 
Ordering InformationProduct Citations
Recommended Support Products:
(click button of application of choice)
WB   IP   IF   siRNA  
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human CASK 8573 Xp11.4 NM_003688 O14936
 300172
Mouse Cask 12361 X A1.1 O70589
 N/A
 
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 Ordering Information
Product NameCatalog #UnitPriceQtyAddFavorites
CASK (C-6) sc-13158 200 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CASK siRNA (h) sc-29920 10 µM $258
CASK siRNA (m) sc-29921 10 µM $258
CASK (h)-PR sc-29920-PR 10 µM $23
CASK (m)-PR sc-29921-PR 10 µM $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CASK shRNA Plasmid (h) sc-29920-SH 20 µg $520
CASK shRNA Plasmid (m) sc-29921-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
CASK shRNA (h) Lentiviral Particles sc-29920-V 200 µl $625
CASK shRNA (m) Lentiviral Particles sc-29921-V 200 µl $625
 WB Positive Control Cell Lysates (click product name for more information)
Product NameCatalog #UnitPriceQtyAddFavorites
MIA PaCa-2 Cell Lysate sc-2285 500 µg/200 µl $104
mouse brain extract sc-2253 500 µg/200 µl $104
rat brain extract sc-2392 500 µg/200 µl $104
DU 145 Cell Lysate sc-2268 500 µg/200 µl $104
HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104

CASK Background Information
The MAGUK (membrane-associated guanylate kinase homologs) family of proteins contain multiple protein-binding domains and are involved in cell junction organization, tumor suppression, and signaling. CASK (also designated LIN-2) belongs to a MAGUK subfamily which is characterized by a novel domain structure that consists of a calcium/calmodulin- dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is expressed in rat brain where it binds to cell-surface proteins, such as neurexin and syndecan, and is thought to be involved in signaling at neuronal synapses. CASK translocates to the nucleus and interacts with Tbr-1 to form a complex, which binds to a specific DNA sequence (the T-element), and induces the expression of specific genes, including Reelin. CASK displays a transcription regulation function, which appears crucial for cerebrocortical development.

CASK (C-6) Product Citations
See how others have used CASK (C-6): sc-13158 antibody and or CASK (C-6) antibody conjugates.


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CASK (C-6)
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sc-13158
CASK (C-6): sc-13158. Western blot analysis of CASK expression in MIA PaCa-2 (A) whole cell lysate and mouse brain (B) extract.
sc-13158
CASK (C-6): sc-13158. Western blot analysis of CASK expression in RAW 264.7 whole cell lysate.
sc-13158
CASK siRNA (h): sc-29920. Western blot analysis of CASK expression in non-transfected control (A) and CASK siRNA transfected (B) HeLa cells. Blot probed with CASK (C-6): sc-13158. α-actinin (H-2): sc-17829 used as specificity and loading control.
sc-13158
CASK (C-6): sc-13158. Western blot analysis of CASK expression in mouse brain tissue extract.
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