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ARHGAP4 Antibody (E-18): sc-131401

 |  Datasheet

(Based on data analysis)

  • ARHGAP4 Antibody (E-18) is a goat polyclonal IgG provided at 200 µg/ml
  • epitope mapping within an internal region of ARHGAP4 of human origin
  • recommended for detection of ARHGAP4 of mouse, rat and human origin by WB, IF and ELISA; non cross-reactive with other ARHGAP family members
  • blocking peptide, sc-131401 P
 

See additional ARHGAP Antibodies including ARHGAP, ARHGAP1, ARHGAP11B, ARHGAP23, ARHGAP25, ARHGAP4, ARHGAP6, ARHGAP8, ARHGAP9, ARHGAP10, ARHGAP11A, ARHGAP12, ARHGAP17, ARHGAP18, ARHGAP19, ARHGAP20, ARHGAP21, ARHGAP22, ARHGAP24, ARHGAP27, ARHGAP28, ARHGAP29, ARHGAP30, ARHGAP36, ARHGAP39 and ARHGAP42.

Ordering InformationGene Info
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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
ARHGAP4 Antibody (E-18) sc-131401 200 µg/ml $279
ARHGAP4 (E-18) P sc-131401 P
(peptide)
100 µg/0.5 ml $61
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human ARHGAP4 393 Xq28 NM_001164741, NM_001666 P98171
300023
Mouse Arhgap4 171207 X A7.3 NM_001162423, NM_001162424, NM_138630 NP_619536
N/A
 


ARHGAP4 (Rho GTPase activating protein 4), also known as RGC1 (Rho-GAP hematopoietic protein C1), C1, p115 or RhoGAP4, is a cytoplasmic protein belonging to the Rho GTPase activating protein family. ARHGAP4 contains one Rho-GAP domain, one FCH (Fps/Fes/Fer/CIP4 homology) domain and one SH3 (Src homology 3) domain. Highest expression levels of ARHGAP4 are found in hematopoietic cells, however, it can also be found in lung, placenta and some fetal tissues. ARHGAP4 localizes to the leading edge in migrating cells, axons and growth cones and is believed to participate as an inhibitor of cell motility and axon outgrowth through its regulation of cytoskeletal dynamics. In addition, ARHGAP4 is capable of inhibiting the activity Rho GTPases, such as Cdc42 and Rac 1, that function to promote cell motility and axon outgrowth.