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Bestrophin-4 Antibody (O-21): sc-130974

 |  Datasheet

(Based on data analysis)

  • Bestrophin-4 Antibody (O-21) is a rabbit polyclonal IgG provided at 100 µg/ml
  • recommended for detection of Bestrophin-4 of human origin by WB, IP and ELISA; also reactive with additional species, including canine
 

See additional Bestrophin Antibodies including Bestrophin, Bestrophin-2, Bestrophin-3 and Bestrophin-4.

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 Ordering Information
Product NameCatalog #UnitPriceQtyAdd 
Bestrophin-4 Antibody (O-21) sc-130974 100 µg/ml $279
 siRNA Gene Silencers (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Bestrophin-4 siRNA (h) sc-72643 10 µM $258
Bestrophin-4 (h)-PR sc-72643-PR 10 µM, 20 µl $23
 shRNA Plasmids (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Bestrophin-4 shRNA Plasmid (h) sc-72643-SH 20 µg $520
 shRNA Lentiviral Particles (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Bestrophin-4 shRNA (h) Lentiviral Particles sc-72643-V 200 µl $625
 WB Positive Control Cell Lysate (click product name for more information)
Product NameCatalog #UnitPriceQtyAdd 
Hep G2 Cell Lysate sc-2227 500 µg/200 µl $104
 
Species Gene Name Gene ID Chromosome Location Isoform (mRNA) Accession # Protein Accession # OMIM™ Number
Human BEST4 266675 1p34.1 Q8NFU0
 607336
 

Bestrophin-4, also known as BEST4 or VMD2L2 (Vitelliform macular dystrophy 20-like protein 2), is a 473 amino acid member of the Bestrophin family of proteins. Members of the Bestrophin family are transmembrane proteins that contain a high percentage of aromatic residues, a conserved RFP (Arg-Phe-Pro) motif and they function as anion channels. Bestrophin-4 acts as a calcium-sensitive chloride channel located in the cell membrane. It is believed that Bestrophin-4 also acts as a channel for other physiologically significant anions, such as bicarbonate. Bestrophin-4 is predominantly expressed in the colon, but can be found at low levels in testis, placenta, trachea, spinal chord, lung and retina.

Bestrophin-4 Antibody (O-21) Data
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sc-130974
Bestrophin-4 (O-21): sc-130974. Western blot analysis of Bestrophin-4 expression in Hep G2 whole cell lysate.
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